Mycobacterium tuberculosis: An Adaptable Pathogen Associated With Multiple Human Diseases

Q Chai, Y Zhang, CH Liu - Frontiers in cellular and infection …, 2018 - frontiersin.org
Mycobacterium tuberculosis, the etiological agent of tuberculosis (TB), is an extremely
successful pathogen that adapts to survive within the host. During the latency phase of …

Host directed therapies for tuberculosis: futures strategies for an ancient disease

I Palucci, G Delogu - Chemotherapy, 2018 - karger.com
The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …

Alternation of gut microbiota in patients with pulmonary tuberculosis

M Luo, Y Liu, P Wu, DX Luo, Q Sun, H Zheng… - Frontiers in …, 2017 - frontiersin.org
One-third of the world's population has been infected with Mycobacterium tuberculosis (M.
tuberculosis), a primary pathogen of the mammalian respiratory system, while about 10% of …

Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy

S Namasivayam, M Maiga, W Yuan, V Thovarai… - Microbiome, 2017 - Springer
Abstract Background Effective treatment of Mycobacterium tuberculosis (Mtb) infection
requires at least 6 months of daily therapy with multiple orally administered antibiotics …

The microbiome and tuberculosis: state of the art, potential applications, and defining the clinical research agenda

CC Naidoo, GR Nyawo, BG Wu, G Walzl… - The Lancet …, 2019 - thelancet.com
The diverse microbial communities within our bodies produce metabolites that modulate
host immune responses. Even the microbiome at distal sites has an important function in …

Leptotrichia species in human infections II

ERK Eribe, I Olsen - Journal of oral microbiology, 2017 - Taylor & Francis
Leptotrichia species are non-motile facultative anaerobic/anaerobic bacteria that are found
mostly in the oral cavity and some other parts of the human body, in animals, and even in …

Insights into the unique lung microbiota profile of pulmonary tuberculosis patients using metagenomic next-generation sequencing

G **ao, Z Cai, Q Guo, T Ye, Y Tang, P Guan… - Microbiology …, 2022 - Am Soc Microbiol
The microbiota plays an important role in human health and disease development. The lung
microbiota profile in pulmonary tuberculosis (TB) patients and the effects of anti-TB treatment …

[HTML][HTML] The role of microbiota in respiratory health and diseases, particularly in tuberculosis

T Shah, Z Shah, Z Baloch, XM Cui - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Trillions of beneficial and hostile microorganisms live in the human respiratory and
gastrointestinal tracts, which act as gatekeepers in maintaining human health, ie, protecting …

Microbiome-immune interactions in tuberculosis

G Mori, M Morrison, A Blumenthal - PLoS pathogens, 2021 - journals.plos.org
Tuberculosis (TB) remains an infectious disease of global significance and a leading cause
of death in low-and middle-income countries. Significant effort has been directed towards …

New players in immunity to tuberculosis: the host microbiome, lung epithelium, and innate immune cells

N Gupta, R Kumar, B Agrawal - Frontiers in immunology, 2018 - frontiersin.org
Tuberculosis (TB) is a highly contagious infection and devastating chronic disease, causing
10.4 million new infections and 1.8 million deaths every year globally. Efforts to control and …