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Rho GTPases and signaling networks
L Van Aelst, C D'Souza-Schorey - Genes & development, 1997 - genesdev.cshlp.org
The Rho GTPases form a subgroup of the Ras superfamily of 20-to 30-kD GTP-binding
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
proteins that have been shown to regulate a wide spectrum of cellular functions. These …
Cell polarization and cytokinesis in budding yeast
E Bi, HO Park - Genetics, 2012 - academic.oup.com
Asymmetric cell division, which includes cell polarization and cytokinesis, is essential for
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …
generating cell diversity during development. The budding yeast Saccharomyces cerevisiae …
Cdc42: an essential Rho-type GTPase controlling eukaryotic cell polarity
DI Johnson - Microbiology and Molecular Biology Reviews, 1999 - journals.asm.org
Cdc42p is an essential GTPase that belongs to the Rho/Rac subfamily of Ras-like GTPases.
These proteins act as molecular switches by responding to exogenous and/or endogenous …
These proteins act as molecular switches by responding to exogenous and/or endogenous …
Central roles of small GTPases in the development of cell polarity in yeast and beyond
HO Park, E Bi - Microbiology and molecular biology reviews, 2007 - journals.asm.org
The establishment of cell polarity is critical for the development of many organisms and for
the function of many cell types. A large number of studies of diverse organisms from yeast to …
the function of many cell types. A large number of studies of diverse organisms from yeast to …
Signaling to the actin cytoskeleton
A Schmidt, MN Hall - Annual review of cell and developmental …, 1998 - annualreviews.org
▪ Abstract The actin cytoskeleton is a highly dynamic network composed of actin polymers
and a large variety of associated proteins. The main functions of the actin cytoskeleton are to …
and a large variety of associated proteins. The main functions of the actin cytoskeleton are to …
Expression and regulation of Lhx6 and Lhx7, a novel subfamily of LIM homeodomain encoding genes, suggests a role in mammalian head development
M Grigoriou, AS Tucker, PT Sharpe… - Development, 1998 - journals.biologists.com
ABSTRACT LIM-homeobox containing (Lhx) genes encode trascriptional regulators which
play critical roles in a variety of developmental processes. We have identified two genes …
play critical roles in a variety of developmental processes. We have identified two genes …
The yeast phosphatidylinositol kinase homolog TOR2 activates RHO1 and RHO2 via the exchange factor ROM2
A Schmidt, M Bickle, T Beck, MN Hall - Cell, 1997 - cell.com
The Saccharomyces cerevisiae phosphatidylinositol kinase homolog TOR2 is required for
organization of the actin cytoskeleton. Overexpression of RHO1 or RHO2, encoding Rho-like …
organization of the actin cytoskeleton. Overexpression of RHO1 or RHO2, encoding Rho-like …
Morphogenesis and the cell cycle
AS Howell, DJ Lew - Genetics, 2012 - academic.oup.com
Studies of the processes leading to the construction of a bud and its separation from the
mother cell in Saccharomyces cerevisiae have provided foundational paradigms for the …
mother cell in Saccharomyces cerevisiae have provided foundational paradigms for the …
Cell polarity in yeast
J Chant - Annual review of cell and developmental biology, 1999 - annualreviews.org
▪ Abstract Subcellular asymmetry, cell polarity, is fundamental to the diverse specialized
functions of eukaryotic cells. In yeast, cell polarization is essential to division and mating. As …
functions of eukaryotic cells. In yeast, cell polarization is essential to division and mating. As …
Role of small G proteins in yeast cell polarization and wall biosynthesis
E Cabib, J Drgonová, T Drgon - Annual review of biochemistry, 1998 - annualreviews.org
In the vegetative (mitotic) cycle and during sexual conjugation, yeast cells display polarized
growth, giving rise to a bud or to a mating projection, respectively. In both cases one can …
growth, giving rise to a bud or to a mating projection, respectively. In both cases one can …