For over a decade, the animal field has led the way in using DNA methylation
measurements to construct epigenetic clocks of aging. These clocks can predict organismal …

How long-lived trees escape “mutational meltdown” despite centuries of continuous growth
remains puzzling. Here we integrate recent studies to show that the yearly rate of somatic …

Long-lived perennial plants accumulate numerous somatic mutations with age. Mutations
originating in stem cells at the shoot apex often become fixed in large sectors of the plant …

Trees are critical components of ecosystems and of major economic importance. Due to their
extraordinary longevity and well-defined modular architecture they have also emerged as …

DNA methylation is crucial for silencing transposable elements and gene regulation. It can
change stochastically, causing" spontaneous epimutations" that may be inherited. This …

Zusammenfassung Die langfristige Perspektive waldwachstumskundlicher Versuche ist
entscheidend, um langfristige Tendenzen zu verstehen und zu gestalten, die die komplexen …

The shoot apical meristem (SAM) is pivotal for plant development, acting as the source of all
aerial tissues and the origin of the gametes. Despite extensive knowledge of the regulation …