Trafficking mechanisms of synaptogenic cell adhesion molecules

LF Ribeiro, B Verpoort, J de Wit - Molecular and Cellular Neuroscience, 2018 - Elsevier
Nearly every aspect of neuronal function, from wiring to information processing, critically
depends on the highly polarized architecture of neurons. Establishing and maintaining the …

Neurexin–Neuroligin 1 regulates synaptic morphology and functions via the WAVE regulatory complex in Drosophila neuromuscular junction

G **ng, M Li, Y Sun, M Rui, Y Zhuang, H Lv, J Han… - elife, 2018 - elifesciences.org
Neuroligins are postsynaptic adhesion molecules that are essential for postsynaptic
specialization and synaptic function. But the underlying molecular mechanisms of neuroligin …

Neuroligin 1, 2, and 3 regulation at the synapse: FMRP-dependent translation and activity-induced proteolytic cleavage

JJ Chmielewska, B Kuzniewska, J Milek… - Molecular …, 2019 - Springer
Neuroligins (NLGNs) are cell adhesion molecules located on the postsynaptic side of the
synapse that interact with their presynaptic partners neurexins to maintain trans-synaptic …

Neuroligin 2 governs synaptic morphology and function through RACK1-cofilin signaling in Drosophila

Y Sun, M Li, J Geng, S Meng, R Tu, Y Zhuang… - Communications …, 2023 - nature.com
Neuroligins are transmembrane cell adhesion proteins well-known for their genetic links to
autism spectrum disorders. Neuroligins can function by regulating the actin cytoskeleton …

[HTML][HTML] Short time-series expression transcriptome data reveal the gene expression patterns of dairy cow mammary gland as milk yield decreased process

Y Fan, Z Han, X Lu, AAI Arbab, M Nazar, Y Yang… - Genes, 2021 - mdpi.com
The existing research on dairy cow mammary gland genes is extensive, but there have been
few reports about dynamic changes in dairy cow mammary gland genes as milk yield …

Proteolytic maturation of Drosophila Neuroligin 3 by tumor necrosis factor α-converting enzyme in the nervous system

J Wu, N Tao, Y Tian, G **ng, H Lv, J Han, C Lin… - … et Biophysica Acta (BBA …, 2018 - Elsevier
Background The functions of autism-associated Neuroligins (Nlgs) are modulated by their
post-translational modifications, such as proteolytic cleavage. A previous study has shown …

Nuclear access of DNlg3 c-terminal fragment and its function in regulating innate immune response genes

H **e, S Liu, Y Fu, Q Cheng, P Wang, CL Bi… - Biochemical and …, 2023 - Elsevier
Neuroligins (NLGNs) are one of the autism susceptibility genes, however, the mechanism
that how dysfunction of NLGNs leads to Autism remains unclear. More and more studies …

[PDF][PDF] Autism is an acquired cellular detoxification deficiency syndrome with heterogeneous genetic predisposition

J Lyons-Weiler - Autism Open Access, 2018 - researchgate.net
Neurodevelopmental disorders, including autism spectrum disorders, have a complex
biological and medical basis involving diverse genetic risk and myriad environmental …

Using structural analysis to clarify the impact of single nucleotide variants in neurexin/neuroligin revealed in clinical genomic sequencing

K Xue, Y Hu, S Gu, C Wang, R Kong… - Journal of Biomolecular …, 2022 - Taylor & Francis
The synapse is a highly specialized and dynamic structure, which is involved in regulating
neurotransmission. Nerve cell adhesion molecule is a kind of transmembrane protein that …

[LLIBRE][B] The Role of the IgSF9 Transmembrane Protein Borderless in Regulating Axonal Transport of Presynaptic Components in Drosophila

HS Shaw - 2019 - search.proquest.com
Normal brain function requires proper targeting of synaptic vesicle (SV) and active zone (AZ)
components for presynaptic assembly and function. Whether and how synaptogenic signals …