Shedding light on the composition of extreme microbial dark matter: alternative approaches for culturing extremophiles

J Schultz, F Modolon, RS Peixoto… - Frontiers in …, 2023 - frontiersin.org
More than 20,000 species of prokaryotes (less than 1% of the estimated number of Earth's
microbial species) have been described thus far. However, the vast majority of microbes that …

Reaching unreachables: Obstacles and successes of microbial cultivation and their reasons

G Kapinusova, MA Lopez Marin, O Uhlik - Frontiers in Microbiology, 2023 - frontiersin.org
In terms of the number and diversity of living units, the prokaryotic empire is the most
represented form of life on Earth, and yet it is still to a significant degree shrouded in …

Metagenomic insights into microbial community structure and metabolism in alpine permafrost on the Tibetan Plateau

L Kang, Y Song, R Mackelprang, D Zhang… - Nature …, 2024 - nature.com
Permafrost, characterized by its frozen soil, serves as a unique habitat for diverse
microorganisms. Understanding these microbial communities is crucial for predicting the …

Targeted isolation and cultivation of uncultivated bacteria by reverse genomics

KL Cross, JH Campbell, M Balachandran… - Nature …, 2019 - nature.com
Most microorganisms from all taxonomic levels are uncultured. Single-cell genomes and
metagenomes continue to increase the known diversity of Bacteria and Archaea; however …

Actinobacteria from Antarctica as a source for anticancer discovery

LJ Silva, EJ Crevelin, DT Souza, GV Lacerda-Júnior… - Scientific reports, 2020 - nature.com
Although many advances have been achieved to treat aggressive tumours, cancer remains
a leading cause of death and a public health problem worldwide. Among the main …

Plant growth‐promoting and antibacterial activities of cultivable bacteria alive in tobacco field against Ralstonia solanacearum

W Yuan, S Ruan, G Qi, R Wang… - Environmental …, 2022 - Wiley Online Library
Bacterial wilt disease caused by Ralstonia solanacearum leads to decrease of crops yield.
Investigation of cultivable bacteria diversity provides more microbial species for screening …

Actinobacteria and cyanobacteria diversity in terrestrial antarctic microenvironments evaluated by culture-dependent and independent methods

A Rego, F Raio, TP Martins, H Ribeiro… - Frontiers in …, 2019 - frontiersin.org
Bacterial diversity from McMurdo Dry Valleys in Antarctica, the coldest desert on earth, has
become more easily assessed with the development of High Throughput Sequencing (HTS) …

Exploring untapped potential of Streptomyces spp. in Gurbantunggut Desert by use of highly selective culture strategy

S Li, L Dong, WH Lian, ZL Lin, CY Lu, L Xu, L Li… - Science of the Total …, 2021 - Elsevier
Streptomycetes have been, for over 70 years, one of the most abundant sources for the
discovery of new antibiotics and clinic drugs. However, in recent decades, it has been more …

Uncovering the uncultivated majority in Antarctic soils: toward a synergistic approach

S Lambrechts, A Willems, G Tahon - Frontiers in microbiology, 2019 - frontiersin.org
Although Antarctica was once believed to be a sterile environment, it is now clear that the
microbial communities inhabiting the Antarctic continent are surprisingly diverse. Until the …

Isolation and cultivation of human gut microorganisms: A review

X Wan, Q Yang, X Wang, Y Bai, Z Liu - Microorganisms, 2023 - mdpi.com
Microbial resources from the human gut may find use in various applications, such as
empirical research on the microbiome, the development of probiotic products, and …