Targeting glioblastoma stem cells: a review on biomarkers, signal pathways and targeted therapy

X Tang, C Zuo, P Fang, G Liu, Y Qiu, Y Huang… - Frontiers in …, 2021‏ - frontiersin.org
Glioblastoma (GBM) remains the most lethal and common primary brain tumor, even after
treatment with multiple therapies, such as surgical resection, chemotherapy, and radiation …

Role of neutrophils and myeloid-derived suppressor cells in glioma progression and treatment resistance

S Khan, S Mittal, K McGee, KD Alfaro-Munoz… - International journal of …, 2020‏ - mdpi.com
Recent efforts in brain tumor research have been directed towards the modulation of the
immune system for therapeutic interventions. Several human cancers, including gliomas, are …

Contribution of the microenvironmental niche to glioblastoma heterogeneity

IAW Ho, WSN Shim - BioMed Research International, 2017‏ - Wiley Online Library
Glioblastoma is the most aggressive cancer of the brain. The dismal prognosis is largely
attributed to the heterogeneous nature of the tumor, which in addition to intrinsic molecular …

Involvement of NOS2 activity on human glioma cell growth, clonogenic potential, and neurosphere generation

P Palumbo, F Lombardi, G Siragusa… - International journal of …, 2018‏ - mdpi.com
Aberrant nitric oxide synthase 2 (NOS2) expression has been suggested as an interesting
therapeutic target that is being implicated as a component of the molecular profile of several …

Molecular mechanism of Notch signaling with special emphasis on microRNAs: Implications for glioma

D Yan, C Hao, L **ao‐feng, L Yu‐chen… - Journal of cellular …, 2019‏ - Wiley Online Library
Glioma is the most aggressive primary brain tumor and is notorious for resistance to
chemoradiotherapy. Although its associated mechanisms are still not completely …

[HTML][HTML] The implications of nitric oxide metabolism in the treatment of glial tumors

M Mazurek, R Rola - Neurochemistry International, 2021‏ - Elsevier
Glial tumors are the most common intracranial malignancies. Unfortunately, despite such a
high prevalence, patients' prognosis is usually poor. It is related to the high invasiveness …

[HTML][HTML] Emerging roles of inhibitor of differentiation-1 in Alzheimer's disease: cell cycle reentry and beyond

SD Chen, JL Yang, YC Lin, AC Chao, DI Yang - Cells, 2020‏ - mdpi.com
Inhibitor of DNA-binding/differentiation (Id) proteins, a family of helix-loop-helix (HLH)
proteins that includes four members of Id1 to Id4 in mammalian cells, are critical for …

Id proteins: emerging roles in CNS disease and targets for modifying neural stemcell behavior

YH Chu, J Lin, S Nath, C Schachtrup - Cell and Tissue Research, 2022‏ - Springer
Neural stem/progenitor cells (NSPCs) are found in the adult brain and spinal cord, and
endogenous or transplanted NSPCs contribute to repair processes and regulate immune …

Emerging novel mechanisms of action for nitric oxide in cancer progression

SA Glynn - Current Opinion in Physiology, 2019‏ - Elsevier
Highlights•This review gives an overview of recent research on the role of nitric oxide in
cancer development and progression.•Describes the role of nitric oxide in cancer …

Research on data mining algorithm based on pattern recognition

X Zhang - International Journal of Pattern Recognition and …, 2020‏ - World Scientific
With the advent of the era of big data, people are eager to extract valuable knowledge from
the rapidly expanding data, so that they can more effectively use these massive storage …