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Signaling pathways in cancer metabolism: mechanisms and therapeutic targets
M You, Z **e, N Zhang, Y Zhang, D **ao, S Liu… - Signal transduction and …, 2023 - nature.com
A wide spectrum of metabolites (mainly, the three major nutrients and their derivatives) can
be sensed by specific sensors, then trigger a series of signal transduction pathways and …
be sensed by specific sensors, then trigger a series of signal transduction pathways and …
Genetic and biological drivers of prostate cancer disparities in Black men
J Gong, DM Kim, MR Freeman, H Kim, L Ellis… - Nature Reviews …, 2024 - nature.com
Black men with prostate cancer have historically had worse outcomes than white men with
prostate cancer. The causes of this disparity in outcomes are multi-factorial, but a potential …
prostate cancer. The causes of this disparity in outcomes are multi-factorial, but a potential …
Nomogram predicts risk and prognostic factors for bone metastasis of pancreatic cancer: a population-based analysis
W Zhang, L Ji, X Wang, S Zhu, J Luo, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The overall survival (OS) of pancreatic cancer (PC) patients with bone
metastasis (BM) is extremely low, and it is pretty hard to treat bone metastasis. However …
metastasis (BM) is extremely low, and it is pretty hard to treat bone metastasis. However …
A novel ten-gene signature predicting prognosis in hepatocellular carcinoma
T Zhou, Z Cai, N Ma, W **e, C Gao, M Huang… - Frontiers in cell and …, 2020 - frontiersin.org
Hepatocellular carcinoma (HCC) has a dismal long-term outcome. We aimed to construct a
multi-gene model for prognosis prediction to inform HCC management. The cancer-specific …
multi-gene model for prognosis prediction to inform HCC management. The cancer-specific …
Synergistic Regulation of Targeted Organelles in Tumor Cells to Promote Photothermal‐Immunotherapy Using Intelligent Core‐Satellite‐Like Nanoparticles for …
X Chang, X Tang, W Tang, L Weng, T Liu, Z Zhu, J Liu… - Small, 2024 - Wiley Online Library
The normal operation of organelles is critical for tumor growth and metastasis. Herein, an
intelligent nanoplatform (BMAEF) is fabricated to perform on‐demand destruction of …
intelligent nanoplatform (BMAEF) is fabricated to perform on‐demand destruction of …
[HTML][HTML] Cellular and molecular progression of prostate cancer: models for basic and preclinical research
Simple Summary The molecular progression of prostate cancer is complex and elusive.
Biological research relies heavily on in vitro and in vivo models that can be used to examine …
Biological research relies heavily on in vitro and in vivo models that can be used to examine …
Circular RNA circ-0016068 promotes the growth, migration, and invasion of prostate cancer cells by regulating the miR-330-3p/BMI-1 axis as a competing …
Q Li, W Wang, M Zhang, W Sun, W Shi… - Frontiers in Cell and …, 2020 - frontiersin.org
Prostate cancer is a common neoplasm worldwide, and the sixth most common cause of
cancer-related mortality. Biomarkers for earlier diagnosis and improved treatment …
cancer-related mortality. Biomarkers for earlier diagnosis and improved treatment …
A novel BMI-1 inhibitor QW24 for the treatment of stem-like colorectal cancer
J Wang, Y **ng, Y Wang, Y He, L Wang, S Peng… - Journal of Experimental …, 2019 - Springer
Background Cancer-initiating cell (CIC), a functionally homogeneous stem-like cell
population, is resonsible for driving the tumor maintenance and metastasis, and is a source …
population, is resonsible for driving the tumor maintenance and metastasis, and is a source …
H2A monoubiquitination links glucose availability to epigenetic regulation of the endoplasmic reticulum stress response and cancer cell death
Epigenetic regulation of gene transcription has been shown to coordinate with nutrient
availability, yet the mechanisms underlying this coordination remain incompletely …
availability, yet the mechanisms underlying this coordination remain incompletely …
LncRNA SNHG3 enhances BMI1 mRNA stability by binding and regulating c‐MYC: Implications for the carcinogenic role of SNHG3 in bladder cancer
The transformation of nonmuscle‐invasive bladder cancer (BLCa) to muscle‐invasive type
and distant metastasis are the two major threats to patients after surgery. Thus, it is important …
and distant metastasis are the two major threats to patients after surgery. Thus, it is important …