Interleukin-18 (IL-18) is a potent pro-inflammatory cytokine involved in host defense against
infections and regulates the innate and acquired immune response. IL-18 is produced by …

Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

Autoimmune diseases are a group of heterogeneous diseases with diverse clinical
manifestations that can be divided into systemic and organ-specific. The common etiology of …

While systemic lupus erythematosus (SLE) is an autoantibody and immune complex disease
by nature, most of its organ manifestations are in fact inflammatory. SLE activity scores thus …

The role of the cytokines and receptors of the IL-1 family in inflammation is well known.
Several cytokines of the family have a powerful inflammatory activity, with IL-1β being the …

Interleukin (IL)-18, a member of the IL-1 superfamily, is a pro-inflammatory cytokine that is
structurally similar to IL-1β. IL-18 promotes the production of interferon gamma (IFN-γ) and …

Interleukins (ILs)—which are important members of cytokines—consist of a vast group of
molecules, including a wide range of immune mediators that contribute to the immunological …

Patients with systemic lupus erythematosus (SLE) display increased numbers of immature
neutrophils in the blood, but the exact role of these immature neutrophils is unclear …

Interleukin (IL)-18 is a pleiotropic, pro-inflammatory cytokine involved in the regulation of
innate and adaptive immune responses. IL-18 has attracted increasing attention as a key …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the
breakdown of immune tolerance leading to excessive inflammation and tissue damage …