Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children

AW Kay, T Ness, SE Verkuijl, K Viney… - Cochrane Database …, 2022 - cochranelibrary.com
Background Every year, an estimated one million children and young adolescents become
ill with tuberculosis, and around 226,000 of those children die. Xpert MTB/RIF Ultra (Xpert …

Xpert MTB/RIF Ultra and Xpert MTB/RIF assays for extrapulmonary tuberculosis and rifampicin resistance in adults

M Kohli, I Schiller, N Dendukuri, M Yao… - Cochrane Database …, 2021 - cochranelibrary.com
Background Xpert MTB/RIF Ultra (Xpert Ultra) and Xpert MTB/RIF are World Health
Organization (WHO)‐recommended rapid nucleic acid amplification tests (NAATs) widely …

[BOOK][B] WHO consolidated guidelines on tuberculosis. Module 5: management of tuberculosis in children and adolescents

World Health Organization - 2022 - books.google.com
The objectives of the 2022 consolidated guidelines are: to provide policy makers and
implementing partners with evidence-based recommendations on the cascade of care for …

[BOOK][B] WHO operational handbook on tuberculosis. Module 5: management of tuberculosis in children and adolescents

World Health Organization - 2022 - books.google.com
The aim of this operational handbook is to provide practical guidance on the implementation
of the World Health Organization (WHO) policy recommendations on the prevention and …

Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis

JS Zifodya, JS Kreniske, I Schiller… - Cochrane Database …, 2021 - cochranelibrary.com
Background Xpert MTB/RIF and Xpert MTB/RIF Ultra (Xpert Ultra) are World Health
Organization (WHO)‐recommended rapid tests that simultaneously detect tuberculosis and …

Transcriptomics for child and adolescent tuberculosis

M Kaforou, C Broderick, O Vito, M Levin… - Immunological …, 2022 - Wiley Online Library
Tuberculosis (TB) in humans is caused by Mycobacterium tuberculosis (Mtb). It is estimated
that 70 million children (< 15 years) are currently infected with Mtb, with 1.2 million each year …

Screening tests for active pulmonary tuberculosis in children

B Vonasek, T Ness, Y Takwoingi… - Cochrane Database …, 2021 - cochranelibrary.com
Background Globally, children under 15 years represent approximately 12% of new
tuberculosis cases, but 16% of the estimated 1.4 million deaths. This higher share of …

[PDF][PDF] Tuberculosis in children

D Jaganath, J Beaudry, N Salazar-Austin - Infectious disease clinics of …, 2022 - Elsevier
The successful care of children and adolescents with TB requires a recognition of the risk
factors and clinical and radiographic signs of TB, especially when microbiologic testing is …

Diagnostic advances in childhood tuberculosis—improving specimen collection and yield of microbiological diagnosis for intrathoracic tuberculosis

E Wobudeya, M Bonnet, EG Walters, P Nabeta, R Song… - Pathogens, 2022 - mdpi.com
There is no microbiological gold standard for childhood tuberculosis (TB) diagnosis. The
paucibacillary nature of the disease, challenges in sample collection in young children, and …

Rapid molecular tests for tuberculosis and tuberculosis drug resistance: a qualitative evidence synthesis of recipient and provider views

N Engel, EA Ochodo, PW Karanja… - Cochrane Database …, 2022 - cochranelibrary.com
Background Programmes that introduce rapid molecular tests for tuberculosis and
tuberculosis drug resistance aim to bring tests closer to the community, and thereby cut …