Microgel-based Modular 3D in vitro microfluidic cell culture platform
The combination of 3D in vitro cell culture and microfluidic technology has emerged as a
powerful tool in biomedical engineering. It offers a more physiologically relevant model …
powerful tool in biomedical engineering. It offers a more physiologically relevant model …
[HTML][HTML] An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing
JW Fleming, MC McCloskey, K Gray, DR Nash… - Current Research in …, 2025 - Elsevier
Animal models of the neuromuscular junction (NMJ) have been widely studied but exhibit
critical differences from human biology limiting utility in drug and disease modelling …
critical differences from human biology limiting utility in drug and disease modelling …
Success and Challenges with Models for Cardiac Translational Research
R Kettenhofen, JC Neubauer - Drug Discovery and Evaluation: Safety and …, 2024 - Springer
Human induced pluripotent stem cells (hiPSCs) are a significant milestone in modern
biology. hiPSCs, being capable of differentiating into any cell type, provide access to all cell …
biology. hiPSCs, being capable of differentiating into any cell type, provide access to all cell …
Comprehensive Collection of Current Methods for Contractility and Electrophysiology Recordings in Human Cardiac Cells
ARTICLES DISCUSSED: Gerges, NA et al. Measurement of heart contractility in isolated
adult human primary cardiomyocytes. Journal of Visualized Experiments.(186), e64394 …
adult human primary cardiomyocytes. Journal of Visualized Experiments.(186), e64394 …
[PDF][PDF] A Scalable Functional Model of 3D Human NeuromuscularJunctionsUsingtheMantarrayPlatform
J Fleming, C Michas - 2024 - downloads.curibio.com
The neuromuscular junction (NMJ) converts nerve signals into muscle contractions and is at
the epicenter of numerous disease pathologies and therapeutic interventions. Despite its …
the epicenter of numerous disease pathologies and therapeutic interventions. Despite its …
[PDF][PDF] Pre-clinical Identification of Dose-Dependent Cardiac Toxicity
S Luttrell, C Michas, J Macadangdang, J Perez - 2024 - downloads.curibio.com
Cardiac toxicity poses a major risk for patients' safety and for the sustainability of drug
development, highlighting the need to identify cardiotoxic side-effects early in the …
development, highlighting the need to identify cardiotoxic side-effects early in the …