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The genetic basis of long QT and short QT syndromes: a mutation update
PL Hedley, P Jørgensen, S Schlamowitz… - Human …, 2009 - Wiley Online Library
Long QT and short QT syndromes (LQTS and SQTS) are cardiac repolarization
abnormalities that are characterized by length perturbations of the QT interval as measured …
abnormalities that are characterized by length perturbations of the QT interval as measured …
Assessing QT interval prolongation and its associated risks with antipsychotics
Several antipsychotics are associated with the ventricular tachycardia torsade de pointes
(TdP), which may lead to sudden cardiac death (SCD), because of their inhibition of the …
(TdP), which may lead to sudden cardiac death (SCD), because of their inhibition of the …
Differentiating drug‐induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil
Block of the hERG potassium channel and prolongation of the QT interval are predictors of
drug‐induced torsade de pointes. However, drugs that block the hERG potassium channel …
drug‐induced torsade de pointes. However, drugs that block the hERG potassium channel …
Association between Tp‐e/QT ratio and prognosis in patients undergoing primary percutaneous coronary intervention for ST‐segment elevation myocardial infarction
X Zhao, Z **e, Y Chu, L Yang, W Xu, X Yang… - Clinical …, 2012 - Wiley Online Library
Abstract Background: Both the Tpeak‐Tend interval (Tp‐e) and the Tp‐e/QT ratio have been
linked to increased risk for arrhythmia. Patient Tp‐e/QT ratios were investigated prior to …
linked to increased risk for arrhythmia. Patient Tp‐e/QT ratios were investigated prior to …
The prognostic value of the Tpeak-Tend interval in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction
INTRODUCTION: The Tpeak-Tend interval (TpTe) has been linked to increased arrhythmic
risk. TpTe was investigated before and after primary percutaneous coronary intervention …
risk. TpTe was investigated before and after primary percutaneous coronary intervention …
Evaluation of index of cardio‐electrophysiological balance (iCEB) as a new biomarker for the identification of patients at increased arrhythmic risk
T Robyns, HR Lu, DJ Gallacher… - Annals of …, 2016 - Wiley Online Library
Background Recently a new risk marker for drug‐induced arrhythmias called index of cardio‐
electrophysiological balance (iCEB), measured as QT interval divided by QRS duration, was …
electrophysiological balance (iCEB), measured as QT interval divided by QRS duration, was …
KCNQ1 long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia
Patients with loss-of-function mutations in KCNQ1 have KCNQ1 long QT syndrome (LQTS).
KCNQ1 encodes a voltage-gated K+ channel located in both cardiomyocytes and pancreatic …
KCNQ1 encodes a voltage-gated K+ channel located in both cardiomyocytes and pancreatic …
Reference values of electrocardiogram repolarization variables in a healthy population
INTRODUCTION: Reference values for T-wave morphology analysis and evaluation of the
relationship with age, sex, and heart rate are lacking in the literature. In this study, we …
relationship with age, sex, and heart rate are lacking in the literature. In this study, we …
Cardiovascular safety of antipsychotics: a clinical overview
C Polcwiartek, K Kragholm, O Schjerning… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Although antipsychotics have been associated with sudden cardiac death
(SCD), they still remain a cornerstone in the treatment of psychiatric patients. Most …
(SCD), they still remain a cornerstone in the treatment of psychiatric patients. Most …
Electrocardiographic predictors of cardiovascular mortality
I Mozos, A Caraba - Disease markers, 2015 - Wiley Online Library
Cardiovascular diseases are the main causes of mortality. Sudden cardiac death may also
appear in athletes, due to underlying congenital or inherited cardiac abnormalities. The …
appear in athletes, due to underlying congenital or inherited cardiac abnormalities. The …