Drug delivery to the brain is crucial in the treatment for central nervous system disorders.
While significant progress has been made in recent years, there are still major challenges in …

Natural living materials serving as biotherapeutics exhibit great potential for treating various
diseases owing to their immunoactivity, tissue targeting, and other biological activities. In this …

High efficacy, selectivity and cellular targeting of therapeutic agents has been an active area
of investigation for decades. Currently, most clinically approved therapeutics are small …

The COVID-19 mRNA vaccine was developed by the scalable manufacture of lipid
nanoparticles (LNPs) that encapsulate mRNA within the lipid. There are many potential …

Introduction A major challenge in treating central nervous system (CNS) disorders is to
achieve adequate drug delivery across the blood–brain barrier (BBB). Receptor-mediated …

New nanotechnology strategies for enhancing drug delivery in brain disorders have recently
received increasing attention from drug designers. The treatment of neurological conditions …

Inflammation and neuroinflammation play critical roles in the pathogenesis of
neurodegenerative diseases such as Parkinson's disease (PD). Nanomaterials with reactive …

Treatment of glioblastoma (GBM) remains challenging due to the presence of blood–brain
barrier (BBB) and tumor heterogeneity. Herein, Au nanosheets (AuNSs) functionalized with …

Recently, neurological disorders have led to a growing global burden of fatalities and
disabilities. The limited capacity for natural self‐regeneration poses a significant challenge …

Orthotopic glioblastoma (GBM) has an aggressive growth pattern and complex
pathogenesis, becoming one of the most common and deadly tumors of the central nervous …