Regulated cell death (RCD) relies on activation and recruitment of pore-forming proteins
(PFPs) that function as executioners of specific cell death pathways: apoptosis regulator …

Bcl-2-associated X protein (BAX) is a critical executioner of mitochondrial regulated cell
death through its lethal activity of permeabilizing the mitochondrial outer membrane (MOM) …

The apoptotic executioner protein BAX and the dynamin‐like protein DRP1 co‐localize at
mitochondria during apoptosis to mediate mitochondrial permeabilization and …

Sustained and intense inflammation is the pathological basis for intervertebral disc
degeneration (IVDD). Effective antagonism or reduction of local inflammatory factors may …

The proteins of the BCL-2 family are known as key regulators of apoptosis, with interactions
between family members determining permeabilisation of the mitochondrial outer …

Macromolecular protein assemblies are of fundamental importance for many processes
inside the cell, as they perform complex functions and constitute central hubs where …

Bilayered membranes separate cells from their surroundings and form boundaries between
intracellular organelles and the cytosol. Gated transport of solutes across membranes …

Solvent paramagnetic relaxation enhancement (sPRE) is a versatile nuclear magnetic
resonance (NMR)-based method that allows characterization of the structure and dynamics …

Mycotoxins, unavoidable contaminants in feed and feed ingredients, have the potential to
influence the incidence and severity of various diseases upon ingestion. Sheep coccidiosis …

Background Acute kidney injury is a common and severe complication of sepsis. Sepsis-
induced acute kidney injury (S-AKI) is an independent risk factor for mortality among sepsis …