Peptide nucleic acid (PNA) stands as one of the most successful artificial oligonucleotide
mimetics. Salient features include the stability of hybridization complexes (either as …

Peptide nucleic acid (PNA) is arguably one of the most successful DNA mimics, despite a
most dramatic departure from the native structure of DNA. The present review summarizes …

Peptide nucleic acid or PNA is a synthetic DNA mimic that contains a sequence of
nucleobases attached to a peptide-like backbone derived from N-2-aminoethylglycine. The …

Peptide nucleic acids containing thymidine and 2-aminopyridine (M) nucleobases formed
stable and sequence selective triple helices with double stranded RNA at physiologically …

We have developed a new fluorescent sensing probe for double-stranded RNA (dsRNA) by
integrating thiazole orange (TO) as a base surrogate into triplex-forming PNA. Our probe …

The diverse biological functions of RNA are determined by the complex structures of RNA
stabilized by both secondary and tertiary interactions. An RNA triplex is an important tertiary …

We have developed a new class of triplex-forming peptide nucleic acid (PNA)-based
fluorogenic probes for sensing of the panhandle structure of the influenza A virus (IAV) RNA …

Peptide nucleic acids (PNAs) have been developed for applications in biotechnology and
therapeutics. There is great potential in the development of chemically modified PNAs or …

RNA-binding small probes with deep-red emission are promising for RNA analysis in
biological media without suffering from background fluorescence. Here benzo [c, d] indole …

Compounds that bind specifically to double‐stranded regions of RNA have potential as
regulators of structure‐based RNA function; however, sequence‐selective recognition of …