The gateway reflex regulates tissue-specific autoimmune diseases
Y Tanaka, I Ohki, K Murakami, S Ozawa… - Inflammation and …, 2024 - Springer
The dynamic interaction and movement of substances and cells between the central
nervous system (CNS) and peripheral organs are meticulously controlled by a specialized …
nervous system (CNS) and peripheral organs are meticulously controlled by a specialized …
Regional neural activation defines a gateway for autoreactive T cells to cross the blood-brain barrier
Y Arima, M Harada, D Kamimura, JH Park, F Kawano… - Cell, 2012 - cell.com
Although it is believed that neural activation can affect immune responses, very little is
known about the neuroimmune interactions involved, especially the regulators of immune …
known about the neuroimmune interactions involved, especially the regulators of immune …
Neurophysiological changes in simulated microgravity: An animal model
Microgravity (MG) is one of the main problems that astronauts have to cope with during
space missions. Long-duration space travel can have detrimental effects on human …
space missions. Long-duration space travel can have detrimental effects on human …
A rat model of arthrofibrosis developed after anterior cruciate ligament reconstruction without rigid joint immobilization
A Kaneguchi, J Ozawa, K Minamimoto… - Connective Tissue …, 2021 - Taylor & Francis
Purpose: Complications including arthrofibrosis have been reported after anterior cruciate
ligament reconstruction (ACLR) even under accelerated rehabilitation. To overcome this, we …
ligament reconstruction (ACLR) even under accelerated rehabilitation. To overcome this, we …
Comprehensive dynamic and kinematic analysis of the rodent hindlimb during over ground walking
J Dienes, B Hicks, C Slater, KD Janson, GJ Christ… - Scientific Reports, 2022 - nature.com
The rat hindlimb is a frequently utilized pre-clinical model system to evaluate injuries and
pathologies impacting the hindlimbs. These studies have demonstrated the translational …
pathologies impacting the hindlimbs. These studies have demonstrated the translational …
Multiscale computational model of Achilles tendon wound healing: Untangling the effects of repair and loading
Mechanical stimulation of the healing tendon is thought to regulate scar anisotropy and
strength and is relatively easy to modulate through physical therapy. However, in vivo …
strength and is relatively easy to modulate through physical therapy. However, in vivo …
Significant mechanical interactions at physiological lengths and relative positions of rat plantar flexors
In situ studies involving supraphysiological muscle lengths and relative positions have
shown that connective tissue linkages connecting adjacent muscles can transmit substantial …
shown that connective tissue linkages connecting adjacent muscles can transmit substantial …
Analysis and modeling of rat gait biomechanical deficits in response to volumetric muscle loss injury
JA Dienes, X Hu, KD Janson, C Slater… - … in Bioengineering and …, 2019 - frontiersin.org
There is currently a substantial volume of research underway to develop more effective
approaches for the regeneration of functional muscle tissue as treatment for volumetric …
approaches for the regeneration of functional muscle tissue as treatment for volumetric …
Kinematic and kinetic gait analysis to evaluate functional recovery in thoracic spinal cord injured rats
CC Diogo, LM da Costa, JE Pereira, V Filipe… - Neuroscience & …, 2019 - Elsevier
The recovery of walking function following spinal cord injury (SCI) is of major importance to
patients and clinicians. In experimental SCI studies, a rat model is widely used to assess …
patients and clinicians. In experimental SCI studies, a rat model is widely used to assess …
Hindlimb unloading affects cortical motor maps and decreases corticospinal excitability
A chronic reduction in neuromuscular activity through prolonged body immobilization of
humans results in muscle atrophy and weakness as well as motor tasks performance …
humans results in muscle atrophy and weakness as well as motor tasks performance …