Exercise can prevent and improve the pathophysiology of diseases and promote healthy
aging. Thus, understanding the mechanisms that regulate the beneficial effects of exercise …

Voluntary physical activity and exercise training can favorably influence brain plasticity by
facilitating neurogenerative, neuroadaptive, and neuroprotective processes. At least some of …

Identifying secreted mediators that drive the cognitive benefits of exercise holds great
promise for the treatment of cognitive decline in ageing or Alzheimer's disease (AD). Here …

Because of intrinsic differences between humans and mice, no single mouse model can
represent all features of a complex human trait such as alcoholism. It is therefore necessary …

Mammals expend energy in many ways, including basic cellular maintenance and repair,
digestion, thermoregulation, locomotion, growth and reproduction. These processes can …

In our target article, we proposed that addiction could be envisioned as misperformance of a
decision-making machinery described by two systems (deliberative and habit systems) …

A model for systematic changes in patterns of inter-individual variation in affective responses
to physical activity of varying intensities is presented, as a conceptual alternative to the …

In recommending physical activity for public health, authors have advocated either an
approach in which the participant is to follow a prescription developed by a professional or …

Numbers of overweight and obese individuals are increasing in the United States and
globally, and, correspondingly, the associated health care costs are rising dramatically …

Physical activity enhances hippocampal function but its effects on neuronal structure remain
relatively unexplored outside of the dentate gyrus. Using Golgi impregnation and the …