Bioactive materials for bone regeneration: biomolecules and delivery systems

A Szwed-Georgiou, P Płociński… - ACS biomaterials …, 2023‏ - ACS Publications
Novel tissue regeneration strategies are constantly being developed worldwide. Research
on bone regeneration is noteworthy, as many promising new approaches have been …

Manufacturing methods, properties, and potential applications in bone tissue regeneration of hydroxyapatite-chitosan biocomposites: A review

HA Said, H Mabroum, M Lahcini, H Oudadesse… - International Journal of …, 2023‏ - Elsevier
Hydroxyapatite (HA) and chitosan (CS) biopolymer are the major materials investigated for
biomedical purposes. Both of these components play an important role in the orthopedic …

Comparing the therapeutic potential of stem cells and their secretory products in regenerative medicine

JB Foo, QH Looi, PP Chong, NH Hassan… - Stem cells …, 2021‏ - Wiley Online Library
Cell therapy involves the transplantation of human cells to replace or repair the damaged
tissues and modulate the mechanisms underlying disease initiation and progression in the …

Strategies for controlled delivery of growth factors and cells for bone regeneration

TN Vo, FK Kasper, AG Mikos - Advanced drug delivery reviews, 2012‏ - Elsevier
The controlled delivery of growth factors and cells within biomaterial carriers can enhance
and accelerate functional bone formation. The carrier system can be designed with pre …

[HTML][HTML] Biomaterials, current strategies, and novel nano-technological approaches for periodontal regeneration

G Iviglia, S Kargozar, F Baino - Journal of functional biomaterials, 2019‏ - mdpi.com
Periodontal diseases involve injuries to the supporting structures of the tooth and, if left
untreated, can lead to the loss of the tooth. Regenerative periodontal therapies aim, ideally …

The role of growth factors in the repair of bone: biology and clinical applications

JR Lieberman, A Daluiski, TA Einhorn - JBJS, 2002‏ - journals.lww.com
➤ There are a number of potential clinical applications for growth factors in the enhancement
of bone repair, including acceleration of fracture-healing, treatment of established …

Novel scaffold platforms for simultaneous induction osteogenesis and angiogenesis in bone tissue engineering: a cutting-edge approach

A Saberi, M Kouhjani, M Mohammadi… - Journal of …, 2023‏ - Springer
Despite the recent advances in the development of bone graft substitutes, treatment of
critical size bone defects continues to be a significant challenge, especially in the elderly …

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

T Rademakers, JM Horvath… - Journal of tissue …, 2019‏ - Wiley Online Library
The field of tissue engineering is making great strides in develo** replacement tissue
grafts for clinical use, marked by the rapid development of novel biomaterials, their improved …

Gene therapy for regenerative medicine

H Hosseinkhani, AJ Domb, G Sharifzadeh, V Nahum - Pharmaceutics, 2023‏ - mdpi.com
The development of biological methods over the past decade has stimulated great interest in
the possibility to regenerate human tissues. Advances in stem cell research, gene therapy …

Microspheres for controlled release drug delivery

NK Varde, DW Pack - Expert opinion on biological therapy, 2004‏ - Taylor & Francis
Controlled release drug delivery employs drug-encapsulating devices from which
therapeutic agents may be released at controlled rates for long periods of time, ranging from …