Point-of-care microfluidic devices for pathogen detection

B Nasseri, N Soleimani, N Rabiee, A Kalbasi… - Biosensors and …, 2018 - Elsevier
The rapid diagnosis of pathogens is crucial in the early stages of treatment of diseases
where the choice of the correct drug can be critical. Although conventional cell culture-based …

Pathogenic mechanisms in HBV-and HCV-associated hepatocellular carcinoma

A Arzumanyan, HM Reis, MA Feitelson - Nature Reviews Cancer, 2013 - nature.com
Hepatocellular carcinoma (HCC) is a highly lethal cancer, with increasing worldwide
incidence, that is mainly associated with chronic hepatitis B virus (HBV) and/or hepatitis C …

[PDF][PDF] Long‐term entecavir treatment reduces hepatocellular carcinoma incidence in patients with hepatitis B virus infection

T Hosaka, F Suzuki, M Kobayashi, Y Seko… - …, 2013 - Wiley Online Library
Chronic hepatitis B virus (HBV) infection leads to cirrhosis and hepatocellular carcinoma
(HCC). Antiviral agents are thought to reduce HCC development, but agents such as …

[HTML][HTML] Guidelines for prevention and treatment of opportunistic infections in HIV-infected adults and adolescents

JE Kaplan, C Benson, KK Holmes, JT Brooks, A Pau… - MMWR Recomm …, 2009 - cdc.gov
This report updates and combines earlier versions of guidelines for the prevention and
treatment of opportunistic infections (OIs) in HIV-infected adults (ie, persons aged> 18 years) …

Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures

D Lavanchy - Journal of viral hepatitis, 2004 - Wiley Online Library
Hepatitis B virus (HBV) infection is a serious global health problem, with 2 billion people
infected worldwide, and 350 million suffering from chronic HBV infection. The 10th leading …

Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level

CJ Chen, HI Yang, JUN Su, CL Jen, SL You, SN Lu… - Jama, 2006 - jamanetwork.com
ContextSerum hepatitis B virus (HBV) DNA level is a marker of viral replication and efficacy
of antiviral treatment in individuals with chronic hepatitis B. ObjectiveTo evaluate the …

[PDF][PDF] Chronic hepatitis B

ASF Lok, BJ McMahon - Hepatology, 2007 - Wiley Online Library
These guidelines have been written to assist physicians and other health care providers in
the recognition, diagnosis, and management of patients chronically infected with the …

Risk estimation for hepatocellular carcinoma in chronic hepatitis B (REACH-B): development and validation of a predictive score

HI Yang, MF Yuen, HLY Chan, KH Han, PJ Chen… - The lancet …, 2011 - thelancet.com
Background Therapy for chronic hepatitis B reduces the risk of progressing to hepatocellular
carcinoma (HCC); however, there is no suitable and accurate means to assess risk. This …

Type 1/Type 2 immunity in infectious diseases

B Spellberg, JE Edwards Jr - Clinical Infectious Diseases, 2001 - academic.oup.com
Abstract T helper type 1 (Th1) lymphocytes secrete secrete interleukin (IL)-2, interferon-γ,
and lymphotoxin-α and stimulate type 1 immunity, which is characterized by intense …

Predicting cirrhosis risk based on the level of circulating hepatitis B viral load

UH Iloeje, HI Yang, J Su, CL Jen, SL You, CJ Chen - Gastroenterology, 2006 - Elsevier
Background & Aims: Cirrhosis develops as a result of hepatic inflammation and subsequent
fibrosis in chronic hepatitis B infection. We report on the relationship between hepatitis B …