A Review on the Immunological Response against Trypanosoma cruzi
Chagas disease is a chronic systemic infection transmitted by Trypanosoma cruzi. Its life
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …
[HTML][HTML] Immunity and vaccine development efforts against Trypanosoma cruzi
Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …
critical lack of methods for prevention of infection or treatment of acute infection and chronic …
Immunization with lipopolysaccharide-activated dendritic cells generates a specific CD8+ T cell response that confers partial protection against infection with …
L Biscari, CD Kaufman, C Farré, V Huhn… - Frontiers in Cellular …, 2022 - frontiersin.org
Lipopolysaccharide (LPS) induces the activation of dendritic cells (DCs) throughout the
engagement of toll-like receptor 4. LPS-activated DCs show increased capacity to process …
engagement of toll-like receptor 4. LPS-activated DCs show increased capacity to process …
Determining seropositivity—A review of approaches to define population seroprevalence when using multiplex bead assays to assess burden of tropical diseases
Background Serological surveys with multiplex bead assays can be used to assess
seroprevalence to multiple pathogens simultaneously. However, multiple methods have …
seroprevalence to multiple pathogens simultaneously. However, multiple methods have …
Preclinical advances and the immunophysiology of a new therapeutic Chagas disease vaccine
Introduction Chronic infection with the protozoal parasite Trypanosoma cruzi leads to a
progressive cardiac disease, known as chronic Chagasic cardiomyopathy (CCC). A new …
progressive cardiac disease, known as chronic Chagasic cardiomyopathy (CCC). A new …
Host‐parasite dynamics in Chagas disease from systemic to hyper‐local scales
Trypanosoma cruzi is a remarkably versatile parasite. It can parasitize almost any nucleated
cell type and naturally infects hundreds of mammal species across much of the Americas. In …
cell type and naturally infects hundreds of mammal species across much of the Americas. In …
The oxidative stress and chronic inflammatory process in Chagas disease: role of exosomes and contributing genetic factors
E Maldonado, DA Rojas, F Urbina… - Oxidative Medicine and …, 2021 - Wiley Online Library
Chagas disease is a neglected tropical disease caused by the flagellated protozoa
Trypanosoma cruzi that affects several million people mainly in Latin American countries …
Trypanosoma cruzi that affects several million people mainly in Latin American countries …
Differential expression profile of genes involved in the immune response associated to progression of chronic Chagas disease
I Gómez, MC López, A Egui, G Palacios… - PLOS Neglected …, 2023 - journals.plos.org
Background Patients with chronic Chagas disease present marked clinical and
immunological heterogeneity. During the disease, multiple immune mechanisms are …
immunological heterogeneity. During the disease, multiple immune mechanisms are …
Aspirin-triggered resolvin D1 reduces parasitic cardiac load by decreasing inflammation in a murine model of early chronic Chagas disease
I Carrillo, RAN Rabelo, C Barbosa… - PLoS Neglected …, 2021 - journals.plos.org
Background Chagas disease, caused by the protozoan Trypanosoma cruzi, is endemic in
Latin America and is widely distributed worldwide because of migration. In 30% of cases …
Latin America and is widely distributed worldwide because of migration. In 30% of cases …
Chagas disease and SARS-CoV-2 coinfection does not lead to worse in-hospital outcomes
I Molina, MS Marcolino, MC Pires, LEF Ramos… - Scientific Reports, 2021 - nature.com
Chagas disease (CD) continues to be a major public health burden in Latina America.
Information on the interplay between COVID-19 and CD is lacking. Our aim was to assess …
Information on the interplay between COVID-19 and CD is lacking. Our aim was to assess …