Neuromodulatory control of complex adaptive dynamics in the brain

JM Shine - Interface focus, 2023 - royalsocietypublishing.org
How is the massive dimensionality and complexity of the microscopic constituents of the
nervous system brought under sufficiently tight control so as to coordinate adaptive …

Response sub-additivity and variability quenching in visual cortex

RLT Goris, R Coen-Cagli, KD Miller… - Nature Reviews …, 2024 - nature.com
Sub-additivity and variability are ubiquitous response motifs in the primary visual cortex (V1).
Response sub-additivity enables the construction of useful interpretations of the visual …

The logic of recurrent circuits in the primary visual cortex

IA Oldenburg, WD Hendricks, G Handy… - Nature …, 2024 - nature.com
Recurrent cortical activity sculpts visual perception by refining, amplifying or suppressing
visual input. However, the rules that govern the influence of recurrent activity remain …

Cell-type-specific plasticity of inhibitory interneurons in the rehabilitation of auditory cortex after peripheral damage

M Kumar, G Handy, S Kouvaros, Y Zhao… - Nature …, 2023 - nature.com
Peripheral sensory organ damage leads to compensatory cortical plasticity that is
associated with a remarkable recovery of cortical responses to sound. The precise …

Gamma oscillation plasticity is mediated via parvalbumin interneurons

MD Hadler, A Tzilivaki, D Schmitz, H Alle… - Science …, 2024 - science.org
Understanding the plasticity of neuronal networks is an emerging field of (patho-)
physiological research, yet the underlying cellular mechanisms remain poorly understood …

Mouse hippocampal CA1 VIP interneurons detect novelty in the environment and support recognition memory

S Tamboli, S Singh, D Topolnik, MEA Barkat… - Cell Reports, 2024 - cell.com
In the CA1 hippocampus, vasoactive intestinal polypeptide-expressing interneurons (VIP-
INs) play a prominent role in disinhibitory circuit motifs. However, the specific behavioral …

Basolateral amygdala oscillations enable fear learning in a biophysical model

A Cattani, DB Arnold, M McCarthy, N Kopell - Elife, 2024 - elifesciences.org
The basolateral amygdala (BLA) is a key site where fear learning takes place through
synaptic plasticity. Rodent research shows prominent low theta (~ 3–6 Hz), high theta (~ 6 …

Top–down modulation in canonical cortical circuits with short-term plasticity

F Waitzmann, YK Wu… - Proceedings of the …, 2024 - National Acad Sciences
Cortical dynamics and computations are strongly influenced by diverse GABAergic
interneurons, including those expressing parvalbumin (PV), somatostatin (SST), and …

VIP interneurons regulate cortical size tuning and visual perception

KA Ferguson, J Salameh, C Alba, H Selwyn, C Barnes… - Cell reports, 2023 - cell.com
Cortical circuit function is regulated by extensively interconnected, diverse populations of
GABAergic interneurons that may play key roles in sha** circuit operation according to …

Untangling stability and gain modulation in cortical circuits with multiple interneuron classes

H Bos, AM Oswald, B Doiron - bioRxiv, 2020 - biorxiv.org
Synaptic inhibition is the mechanistic backbone of a suite of cortical functions, not the least
of which is maintaining overall network stability as well as modulating neuronal gain. Past …