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Ankylosing spondylitis: from cells to genes
JF Zambrano-Zaragoza… - International journal …, 2013 - Wiley Online Library
Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown etiology, though it
is considered an autoimmune disease. HLA‐B27 is the risk factor most often associated with …
is considered an autoimmune disease. HLA‐B27 is the risk factor most often associated with …
[HTML][HTML] The genetics of spondyloarthritis
R Díaz-Peña, P Castro-Santos, J Durán… - Journal of Personalized …, 2020 - mdpi.com
The term spondyloarthritis (SpA) encompasses a group of chronic inflammatory diseases
with common features in terms of clinical presentation and genetic predisposition. SpA is …
with common features in terms of clinical presentation and genetic predisposition. SpA is …
Immunogenomics of killer cell immunoglobulin-like receptor (KIR) and HLA class I: coevolution and consequences for human health
NR Pollock, GF Harrison, PJ Norman - The Journal of Allergy and Clinical …, 2022 - Elsevier
Interactions of killer cell immunoglobin-like receptors (KIR) with human leukocyte antigens
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …
(HLA) class I regulate effector functions of key cytotoxic cells of innate and adaptive …
Activating KIR and HLA Bw4 ligands are associated to decreased susceptibility to pemphigus foliaceus, an autoimmune blistering skin disease
DG Augusto, SC Lobo-Alves, MF Melo, NF Pereira… - PloS one, 2012 - journals.plos.org
The KIR genes and their HLA class I ligands have thus far not been investigated in
pemphigus foliaceus (PF) and related autoimmune diseases, such as pemphigus vulgaris …
pemphigus foliaceus (PF) and related autoimmune diseases, such as pemphigus vulgaris …
Role of KIR3DS1 in human diseases
C Körner, M Altfeld - Frontiers in immunology, 2012 - frontiersin.org
The function of natural killer (NK) cells is controlled by several activating and inhibitory
receptors, including the family of killer-immunoglobulin-like receptors (KIRs). One distinctive …
receptors, including the family of killer-immunoglobulin-like receptors (KIRs). One distinctive …
Significance of KIR like natural killer cell receptors in autoimmune disorders
S Agrawal, S Prakash - Clinical immunology, 2020 - Elsevier
Killer cell immunoglobulin-like receptors (KIRs), act as the regulators for the cytolytic activity
of natural killer and certain T cells by interacting with the HLA class I ligands. KIRs have …
of natural killer and certain T cells by interacting with the HLA class I ligands. KIRs have …
Epistatic interactions between killer immunoglobulin-like receptors and human leukocyte antigen ligands are associated with ankylosing spondylitis
AL Hanson… - PLoS …, 2020 - journals.plos.org
The killer immunoglobulin-like receptors (KIRs), found predominantly on the surface of
natural killer (NK) cells and some T-cells, are a collection of highly polymorphic activating …
natural killer (NK) cells and some T-cells, are a collection of highly polymorphic activating …
[HTML][HTML] A genomic study on distribution of human leukocyte antigen (HLA)-A and HLA-B alleles in Lak population of Iran
F Shahsavar, AM Varzi, SAY Ahmadi - Genomics Data, 2017 - Elsevier
Anthropological studies based on the highly polymorphic gene, human leukocyte antigen
(HLA), provide useful information for bone marrow donor registry, forensic medicine, disease …
(HLA), provide useful information for bone marrow donor registry, forensic medicine, disease …
Activating killer immunoglobulin-like receptors genes are associated with increased susceptibility to ankylosing spondylitis
R Díaz-Peña, JR Vidal-Castiñeira… - Clinical & …, 2015 - academic.oup.com
The aim of this study was to analyse the association of specific killer cell immunoglobulin-
like receptors (KIR) genes and haplotypes with susceptibility to ankylosing spondylitis (AS) …
like receptors (KIR) genes and haplotypes with susceptibility to ankylosing spondylitis (AS) …
MHC genes linked to autoimmune disease
P Deitiker, MZ Atassi - Critical Reviews™ in Immunology, 2015 - dl.begellhouse.com
Autoimmune diseases (ADs), or autoinflammatoiy diseases, are growing in complexity as
diagnoses improve and many factors escalate disease risk. Considerable genetic similarity …
diagnoses improve and many factors escalate disease risk. Considerable genetic similarity …