Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Here, we review recent developments in the literature that provide insight into self-
organization at supracellular scales in vertebrate organ morphogenesis. We briefly present …

Morphogenesis and cell state transitions must be coordinated in time and space to produce
a functional tissue. An excellent paradigm to understand the coupling of these processes is …

Localized sources of morphogens, called signalling centres, play a fundamental role in
coordinating tissue growth and cell fate specification during organogenesis. However, how …

Mechanics is known to play a fundamental role in many cellular and developmental
processes. Beyond active forces and material properties, osmotic pressure is believed to …

Mechanotransduction is a strictly regulated process whereby mechanical stimuli, including
mechanical forces and properties, are sensed and translated into biochemical signals …

Stem cells in organoids self-organize into tissue patterns with unknown mechanisms. Here,
we use skin organoids to analyze this process. Cell behavior videos show that the …

Physical processes ultimately shape tissue during development. Two emerging proposals
are that cells migrate toward stiffer tissue (durotaxis) and that the extent of cell …

Jamming of cell collectives and associated rigidity transitions have been shown to play a key
role in tissue dynamics, structure and morphogenesis. Cellular jamming is controlled by …

The phenomenon of planar cell polarity is critically required for a myriad of morphogenetic
processes in metazoan and is accurately controlled by several conserved modules. Six …