New insights into intracellular locations and functions of heme oxygenase-1

LL Dunn, RG Midwinter, J Ni, HA Hamid… - Antioxidants & redox …, 2014 - liebertpub.com
Abstract Significance: Heme oxygenase-1 (HMOX1) plays a critical role in the protection of
cells, and the inducible enzyme is implicated in a spectrum of human diseases. The …

Redox modulation of adipocyte differentiation: hypothesis of “Redox Chain” and novel insights into intervention of adipogenesis and obesity

X Wang, C Hai - Free Radical Biology and Medicine, 2015 - Elsevier
In view of the global prevalence of obesity and obesity-associated disorders, it is important
to clearly understand how adipose tissue forms. Accumulating data from various laboratories …

Epoxyeicosatrienoic acids regulate adipocyte differentiation of mouse 3T3 cells, via PGC-1α activation, which is required for HO-1 expression and increased …

M Waldman, L Bellner, L Vanella… - Stem cells and …, 2016 - liebertpub.com
Epoxyeicosatrienoic acid (EET) contributes to browning of white adipose stem cells to
ameliorate obesity/diabetes and insulin resistance. In the current study, we show that EET …

Adipocyte-specific expression of PGC1α promotes adipocyte browning and alleviates obesity-induced metabolic dysfunction in an HO-1-Dependent fashion

SH Shen, SP Singh, M Raffaele, M Waldman… - Antioxidants, 2022 - mdpi.com
Recent studies suggest that PGC1-α plays a crucial role in mitochondrial and vascular
function, yet the physiological significance of PGC1α and HO expression in adipose tissues …

Apolipoprotein AI mimetics

ST Reddy, M Navab, GM Anantharamaiah… - Current opinion in …, 2014 - journals.lww.com
Apolipoprotein AI mimetics : Current Opinion in Lipidology Apolipoprotein AI mimetics :
Current Opinion in Lipidology Log in or Register Subscribe to journalSubscribe Get new …

[HTML][HTML] Low levels of ApoA1 improve risk prediction of type 2 diabetes mellitus

X Wu, Z Yu, W Su, DA Isquith, MB Neradilek… - Journal of clinical …, 2017 - Elsevier
Background Type 2 diabetes mellitus (T2DM) has reported to be a major public health crisis
in China. Objective We examined the incidence of new T2DM over 4 years for association of …

Oxidized HDL is a potent inducer of adipogenesis and causes activation of the Ang-II and 20-HETE systems in human obese females

SJ Peterson, L Vanella, K Gotlinger, H Jiang… - Prostaglandins & other …, 2016 - Elsevier
Abstract Background Oxidized-HDL (OX-HDL) has been reported to increase coronary
events in obese patients; however, OX-HDL has not been studied in subjects with the …

RETRACTED ARTICLE: PPARδ binding to heme oxygenase 1 promoter prevents angiotensin II-induced adipocyte dysfunction in Goldblatt hypertensive rats

K Sodhi, N Puri, DH Kim, TD Hinds… - International Journal of …, 2014 - nature.com
Objective: Renin–angiotensin system (RAS) regulates adipogenic response with adipocyte
hypertrophy by increasing oxidative stress. Recent studies have shown the role of …

Combination of 5‐aminolevulinic acid and ferrous ion reduces plasma glucose and hemoglobin A1c levels in Zucker diabetic fatty rats

T Hara, A Koda, N Nozawa, U Ota, H Kondo… - FEBS open …, 2016 - Wiley Online Library
Mitochondrial dysfunction is associated with type 2 diabetes mellitus (T2 DM). 5‐
Aminolevulinic acid (ALA), a natural amino acid produced only in the mitochondria, is a …

ABCA1 agonist peptides for the treatment of disease

JK Bielicki - Current opinion in lipidology, 2016 - journals.lww.com
ABCA1 is an integral membrane protein that plays a central role in biology. Its principal
function is to mediate the efflux of cholesterol and phospholipid from cells to extracellular …