Adipose tissue regeneration: a state of the art

A Casadei, R Epis, L Ferroni, I Tocco… - BioMed Research …, 2012 - Wiley Online Library
Adipose tissue pathologies and defects have always represented a reconstructive challenge
for plastic surgeons. In more recent years, several allogenic and alloplastic materials have …

Impact of diabetes mellitus on human mesenchymal stromal cell biology and functionality: implications for autologous transplantation

M Mahmoud, N Abu-Shahba, O Azmy… - Stem cell reviews and …, 2019 - Springer
Multipotent mesenchymal stem/stromal cells (MSCs) have regenerative and
immunomodulatory properties to restore and repair injured tissues, making them attractive …

[HTML][HTML] Human mesenchymal stem cells exhibit altered mitochondrial dynamics and poor survival in high glucose microenvironment

E Abu-El-Rub, F Almahasneh… - World Journal of Stem …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Mesenchymal stem cells (MSCs) are a type of stem cells that possess
relevant regenerative abilities and can be used to treat many chronic diseases. Diabetes …

Impact of type 2 diabetes mellitus on the immunoregulatory characteristics of adipose tissue-derived mesenchymal stem cells

N Abu-Shahba, M Mahmoud, AM El-Erian… - The international journal …, 2021 - Elsevier
Background Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder associated
with several complications. Adipose tissue-derived mesenchymal stem cells (AT-MSCs) …

Immunogenicity of allogeneic mesenchymal stem cells transplanted via different routes in diabetic rats

LH Gu, TT Zhang, Y Li, HJ Yan, H Qi… - Cellular & molecular …, 2015 - nature.com
Due to their hypoimmunogenicity and unique immunosuppressive properties, mesenchymal
stem cells (MSCs) are considered one of the most promising adult stem cell types for cell …

[BOOK][B] Mass production of mesenchymal stem cells—impact of bioreactor design and flow conditions on proliferation and differentiation

V Jossen, R Pörtner, SC Kaiser, M Kraume, D Eibl… - 2014 - books.google.com
Stem cells have enormous potential in health and medical research due to their ability to
differentiate into specialized cells and to self-renew. Applications can be seen in cell-based …

Angiogenic and restorative abilities of human mesenchymal stem cells were reduced following treatment with serum from diabetes mellitus type 2 patients

J Rezaie, MS Mehranjani… - Journal of cellular …, 2018 - Wiley Online Library
This experiment investigated the impact of serum from patients with type 2 diabetes mellitus
on the angiogenic behavior of human mesenchymal stem cells in vitro. Changes in the level …

Effects of Different Basal Cell Culture Media upon the Osteogenic Response of hMSCs Evaluated by 99mTc-HDP Labeling

T Grossner, U Haberkorn, J Hofmann… - International Journal of …, 2022 - mdpi.com
The osteogenic differentiation of mesenchymal stem cells is now a standard procedure in
modern bone tissue engineering. As this is a promising field for future clinical applications …

O‐Glc NA cylation: a bridge between glucose and cell differentiation

C Sun, J Shang, Y Yao, X Yin, M Liu… - Journal of cellular …, 2016 - Wiley Online Library
Glucose is the major energy supply and a critical metabolite for most cells and is especially
important when cell is differentiating. High or low concentrations of glucose enhances or …

Revisiting MSC expansion from critical quality attributes to critical culture process parameters

C Martin, E Olmos, ML Collignon, N De Isla… - Process …, 2017 - Elsevier
With over 300 clinical trials registered in 2013 and more than 20,000 hits on the NCBI
database, human multipotent stromal cells (hMSC) are widely used and studied as a model …