Collective intelligence: A unifying concept for integrating biology across scales and substrates

P McMillen, M Levin - Communications Biology, 2024 - nature.com
A defining feature of biology is the use of a multiscale architecture, ranging from molecular
networks to cells, tissues, organs, whole bodies, and swarms. Crucially however, biology is …

Soft actuators for soft robotic applications: A review

N El-Atab, RB Mishra, F Al-Modaf… - Advanced Intelligent …, 2020 - Wiley Online Library
Soft robotics technologies are paving the way toward robotic abilities which are vital for a
wide range of applications, including manufacturing, manipulation, grip**, human …

Bioelectric signaling: Reprogrammable circuits underlying embryogenesis, regeneration, and cancer

M Levin - Cell, 2021 - cell.com
How are individual cell behaviors coordinated toward invariant large-scale anatomical
outcomes in development and regeneration despite unpredictable perturbations …

Microfluidic formulation of topological hydrogels for microtissue engineering

KO Rojek, M Cwiklinska, J Kuczak… - Chemical …, 2022 - ACS Publications
Microfluidics has recently emerged as a powerful tool in generation of submillimeter-sized
cell aggregates capable of performing tissue-specific functions, so-called microtissues, for …

[HTML][HTML] The horizon of bone organoid: A perspective on construction and application

S Chen, X Chen, Z Geng, J Su - Bioactive Materials, 2022 - Elsevier
Bone defects repair and regeneration by various causes such as tumor resection, trauma,
degeneration, etc. have always been a key issue in the clinics. As one of the few organs that …

Foundations of gastrointestinal-based drug delivery and future developments

JN Chu, G Traverso - Nature Reviews Gastroenterology & Hepatology, 2022 - nature.com
Gastrointestinal-based drug delivery is considered the preferred mode of drug
administration owing to its convenience for patients, which improves adherence. However …

The bioprinting roadmap

W Sun, B Starly, AC Daly, JA Burdick, J Groll… - …, 2020 - iopscience.iop.org
This bioprinting roadmap features salient advances in selected applications of the technique
and highlights the status of current developments and challenges, as well as envisioned …

Organoids: a systematic review of ethical issues

D De Jongh, EK Massey, EM Bunnik - Stem Cell Research & Therapy, 2022 - Springer
Organoids are 3D structures grown from pluripotent stem cells derived from human tissue
and serve as in vitro miniature models of human organs. Organoids are expected to …

Vascularized organoids on a chip: strategies for engineering organoids with functional vasculature

S Zhang, Z Wan, RD Kamm - Lab on a Chip, 2021 - pubs.rsc.org
Human organoids, self-organized and differentiated from homogenous pluripotent stem cells
(PSC), replicate the key structural and functional characteristics of their in vivo counterparts …

Kinematic self-replication in reconfigurable organisms

S Kriegman, D Blackiston, M Levin… - Proceedings of the …, 2021 - pnas.org
All living systems perpetuate themselves via growth in or on the body, followed by splitting,
budding, or birth. We find that synthetic multicellular assemblies can also replicate …