[HTML][HTML] The aryl hydrocarbon receptor as a target of environmental stressors–Implications for pollution mediated stress and inflammatory responses

CFA Vogel, LS Van Winkle, C Esser… - Redox biology, 2020 - Elsevier
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the
expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) …

Aryl hydrocarbon receptor: Its roles in physiology

Z Kou, W Dai - Biochemical pharmacology, 2021 - Elsevier
Aryl hydrocarbon receptor (AHR) was initially discovered as a cellular protein involved in
mediating the detoxification of xenobiotic compounds. Extensive research in the past two …

Environmental contaminants and congenital heart defects: a re-evaluation of the evidence

R Nicoll - International journal of environmental research and …, 2018 - mdpi.com
Congenital heart defects (CHDs) are a common birth defect of largely unknown etiology,
with high fetal and neonatal mortality. A review of CHDs and environmental contaminant …

Serum biomarkers from cell-based assays for AhRL and MIS strongly predicted the future development of diabetes in a large community-based prospective study in …

HK Lee, WH Park, YC Kang, S Kang, S Im, S Park… - Scientific reports, 2020 - nature.com
Exposure to environment-polluting chemicals (EPC) is associated with the development of
diabetes. Many EPCs exert toxic effects via aryl hydrocarbon receptor (AhR) and/or …

The aryl hydrocarbon receptor undergoes chaperone-mediated autophagy in triple-negative breast cancer cells

J Chen, Y Yang, WA Russu, WK Chan - International Journal of Molecular …, 2021 - mdpi.com
The aryl hydrocarbon receptor (AHR) is a ligand-activated signaling molecule expressed in
many cell types, including triple-negative and non-triple-negative breast cancer cells. It …

Regulation and Functions of Aryl Hydrocarbon Receptor Under Environmental Oxidative Stress

Z Kou - 2023 - search.proquest.com
Aryl hydrocarbon receptor (AhR) was initially discovered as a cellular protein involved in
mediating the detoxification of xenobiotic compounds. While most environmental exposure …

The Aryl Hydrocarbon Receptor as an Environmental Sensor and Mediator of Stress and Inflammation

CFA Vogel, T Haarmann-Stemmann - … and OxInflammatory Tissues …, 2024 - taylorfrancis.com
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor regulating the
expression of genes, for instance encoding the monooxygenases cytochrome P450 (CYP) …

Regulation of Intracellular Aryl Hydrocarbon Receptor Protein Levels

J Chen - 2020 - search.proquest.com
The aryl hydrocarbon receptor (AHR) is a ligand-activated signaling molecule which controls
tumor growth and metastasis, T cell differentiation, and liver development. Expression levels …

Dioxin Impact on Cardiac Development, Structure, Function, and Health, and Implications for Disease

MK de Gannes - 2020 - search.proquest.com
The focus of this dissertation is the characterization of the epigenetic, structural, and
functional consequences of exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD; …

Enhanced Serum AhF Bioactivity and Mitochondrial Inhibition Potential Predict the Development of Diabetes: A Nested Case-Control Study of the Korean Population …

HK Lee, WH Park, YC Kang, S Park… - Available at SSRN …, 2018 - papers.ssrn.com
Background: Exposure to persistent organic pollutants (POPs), some of which are aryl
hydrocarbon receptor (AhR) ligands, is suspected to cause diabetes mellitus (DM). Our …