The in vivo fate of polymeric micelles

Y Cai, J Qi, Y Lu, H He, W Wu - Advanced Drug Delivery Reviews, 2022 - Elsevier
This review aims to provide a systemic analysis of the in vivo, as well as subcellular, fate of
polymeric micelles (PMs), starting from the entry of PMs into the body. Few PMs are able to …

[HTML][HTML] Exploration and insights into the cellular internalization and intracellular fate of amphiphilic polymeric nanocarriers

S Mazumdar, D Chitkara, A Mittal - Acta Pharmaceutica Sinica B, 2021 - Elsevier
The beneficial or deleterious effects of nanomedicines emerge from their complex
interactions with intracellular pathways and their subcellular fate. Moreover, the dynamic …

Smart Design of Nanomaterials for Mitochondria‐Targeted Nanotherapeutics

SS Liew, X Qin, J Zhou, L Li, W Huang… - Angewandte Chemie …, 2021 - Wiley Online Library
Mitochondria are the powerhouse of cells. They are vital organelles that maintain cellular
function and metabolism. Dysfunction of mitochondria results in various diseases with a …

Amphiphilic polymeric nanoparticles encapsulating curcumin: Antioxidant, anti-inflammatory and biocompatibility studies

GM Pontes-Quero, L Benito-Garzón, JP Cano… - Materials Science and …, 2021 - Elsevier
Oxidative stress and inflammation are two related processes common to many diseases.
Curcumin is a natural compound with both antioxidant and anti-inflammatory properties …

Morphological Transformation and In Situ Polymerization of Caspase‐3 Responsive Diacetylene‐Containing Lipidated Peptide Amphiphile for Self‐Amplified …

T Ma, R Chen, N Lv, Y Li, ZR Yang, H Qin, Z Li, H Jiang… - Small, 2022 - Wiley Online Library
In order to artificially regulate cell behaviors, intracellular polymerization as an emerging
chemical technique has attracted much attention. Yet, it is still a challenge to achieve …

Copolymeric micelles of poly (ε-caprolactone) and poly (methacrylic acid) as carriers for the oral delivery of resveratrol

K Kamenova, L Radeva, S Konstantinov, PD Petrov… - Polymers, 2023 - mdpi.com
In this study, we report the development of a micellar system based on a poly (methacrylic
acid)-b-poly (ε-caprolactone)-b-poly (methacrylic acid) triblock copolymer (PMAA16-b …

Development of pH-Responsive N-benzyl-N-O-succinyl Chitosan Micelles Loaded with a Curcumin Analog (Cyqualone) for Treatment of Colon Cancer

S Sripetthong, FN Eze, W Sajomsang, C Ovatlarnporn - Molecules, 2023 - mdpi.com
This work aimed at preparing nanomicelles from N-benzyl-N, O-succinyl chitosan (NBSCh)
loaded with a curcumin analog, 2, 6-bis ((3-methoxy-4-hydroxyphenyl) methylene) …

Green synthesis and the evaluation of a functional amphiphilic block copolymer as a micellar curcumin delivery system

R Kalinova, G Grancharov, J Doumanov… - International Journal of …, 2023 - mdpi.com
Polymer micelles represent one of the most attractive drug delivery systems due to their
design flexibility based on a variety of macromolecular synthetic methods. The …

Curcumin: novel treatment in neonatal hypoxic-ischemic brain injury

E Rocha-Ferreira, C Sisa, S Bright, T Fautz… - Frontiers in …, 2019 - frontiersin.org
Hypoxic-ischemic encephalopathy (HIE) is a major cause of mortality and morbidity in
neonates, with an estimated global incidence of 3/1,000 live births. HIE brain damage is …

Photo-physical, theoretical and photo-cytotoxic evaluation of a new class of lanthanide (III)–curcumin/diketone complexes for PDT application

D Musib, M Pal, MK Raza, M Roy - Dalton Transactions, 2020 - pubs.rsc.org
Herein we report the synthesis, characterization, photophysical and photocytotoxicity studies
of a new class of curcumin-based lanthanide (III) complexes of general molecular formula …