Abstract The Genome Sequence Archive (GSA) is a data repository for archiving raw
sequence data, which provides data storage and sharing services for worldwide scientific …

The recent advent of sophisticated technologies like sequencing and mass spectroscopy
platforms combined with artificial intelligence-powered analytic tools has initiated a new era …

Abstract KaKs_Calculator 3.0 is an updated toolkit that is capable of calculating selective
pressure on both coding and non-coding sequences. Similar to the nonsynonymous …

When cells are stressed, DNA from energy-producing mitochondria can leak out and drive
inflammatory immune responses if not cleared. Cells employ a quality control system called …

Abstract The National Genomics Data Center (NGDC), part of the China National Center for
Bioinformation (CNCB), provides a family of database resources to support global research …

Metabolic fitness of T cells is essential for their vitality, which is largely dependent on the
behavior of the mitochondria. The nature of mitochondrial behavior in tumor-infiltrating T …

Arabidopsis thaliana is an important and long-established model species for plant molecular
biology, genetics, epigenetics, and genomics. However, the latest version of reference …

Viruses significantly influence local and global biogeochemical cycles and help bacteria to
survive in different environments by encoding various auxiliary metabolic genes (AMGs) …

Super-enhancers (SEs) are cell-specific DNA cis-regulatory elements that can supervise the
transcriptional regulation processes of downstream genes. SEdb 2.0 (http://www. licpathway …

Abstract The 2022 Nucleic Acids Research Database Issue contains 185 papers, including
87 papers reporting on new databases and 85 updates from resources previously published …