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Clinical course of multiple sclerosis
The 1996 originally established multiple sclerosis (MS) subtypes, based solely on clinical
impression and consensus, were revised in 2013 to review potential imaging and biological …
impression and consensus, were revised in 2013 to review potential imaging and biological …
MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines
In patients presenting with a clinically isolated syndrome, MRI can support and substitute
clinical information in the diagnosis of multiple sclerosis by showing disease dissemination …
clinical information in the diagnosis of multiple sclerosis by showing disease dissemination …
Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories
CC Gross, A Schulte-Mecklenbeck… - Science Translational …, 2024 - science.org
One of the biggest challenges in managing multiple sclerosis is the heterogeneity of clinical
manifestations and progression trajectories. It still remains to be elucidated whether this …
manifestations and progression trajectories. It still remains to be elucidated whether this …
MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 2: epidemiology, clinical presentation, radiological and laboratory features, treatment …
Background A subset of patients with neuromyelitis optica spectrum disorders (NMOSD) has
been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies (MOG …
been shown to be seropositive for myelin oligodendrocyte glycoprotein antibodies (MOG …
Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria
The 2010 McDonald criteria for the diagnosis of multiple sclerosis are widely used in
research and clinical practice. Scientific advances in the past 7 years suggest that they might …
research and clinical practice. Scientific advances in the past 7 years suggest that they might …
A comprehensive review of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS) is a late-onset fatal neurodegenerative disease affecting
motor neurons with an incidence of about 1/100,000. Most ALS cases are sporadic, but 5 …
motor neurons with an incidence of about 1/100,000. Most ALS cases are sporadic, but 5 …
The radiologically isolated syndrome: revised diagnostic criteria
The radiologically isolated syndrome (RIS) was defined in 2009 as the presence of
asymptomatic, incidentally identified demyelinating-appearing white matter lesions in the …
asymptomatic, incidentally identified demyelinating-appearing white matter lesions in the …
Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans
Neuroinflammation is a pathophysiological hallmark of multiple sclerosis and has a close
mechanistic link to neurodegeneration. Although this link is potentially targetable, robust …
mechanistic link to neurodegeneration. Although this link is potentially targetable, robust …
The central vein sign and its clinical evaluation for the diagnosis of multiple sclerosis: a consensus statement from the North American Imaging in Multiple Sclerosis …
Over the past few years, MRI has become an indispensable tool for diagnosing multiple
sclerosis (MS). However, the current MRI criteria for MS diagnosis have imperfect sensitivity …
sclerosis (MS). However, the current MRI criteria for MS diagnosis have imperfect sensitivity …
Defining high, medium and low impact prognostic factors for develo** multiple sclerosis
Natural history studies have identified factors that predict evolution to multiple sclerosis or
risk of disability accumulation over time. Although these studies are based on large …
risk of disability accumulation over time. Although these studies are based on large …