Titanium (Ti) and its alloys have been widely used as orthopedic implants, because of their
favorable mechanical properties, corrosion resistance and biocompatibility. Despite their …

Several studies suggest that oral pathogenic biofilms cause persistent oral infections.
Among these is periodontitis, a prevalent condition brought on by plaque biofilm. It can even …

The treatment of difficult-to-heal wounds remains a substantial clinical challenge due to
deteriorative tissue microenvironment including the loss of extracellular matrix (ECM) …

Drug delivery systems composed of osteogenic substances and biological materials are of
great significance in enhancing bone regeneration, and appropriate biological carriers are …

The goal of a biomaterial is to support the bone tissue regeneration process at the defect site
and eventually degrade in situ and get replaced with the newly generated bone tissue …

The combination of photothermal therapy (PTT) and gene therapy (GT) shows great
potential to achieve synergistic anti-tumor activity. However, the lack of a controlled release …

The treatment of bone defects remains one of the major challenges in modern clinical
practice. Nowadays, with the increased incidence of bone disease in an aging population …

The failure to repair critical‐sized bone defects often leads to incomplete regeneration or
fracture non‐union. Tissue‐engineered grafts have been recognized as an alternative …

Ideal titanium implants are required to participate in bone repair actively to improve in situ
osteointegration. However, the traditional surface functionalization methods of titanium …

Inorganic/organic hybrid nanosystems have been increasingly developed for their versatility
and efficacy at overcoming obstacles not readily surmounted by nonhybridized counterparts …