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Adverse events in clinical treatments with serotonergic psychedelics and MDMA: A mixed-methods systematic review
JJ Breeksema, BW Kuin, J Kamphuis… - Journal of …, 2022 - journals.sagepub.com
Introduction: Small-scale clinical studies with psychedelic drugs have shown promising
results for the treatment of several mental disorders. Before psychedelics become registered …
results for the treatment of several mental disorders. Before psychedelics become registered …
Serotonin 2A Receptor (5-HT2AR) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants
W Duan, D Cao, S Wang, J Cheng - Chemical Reviews, 2023 - ACS Publications
Psychedelics make up a group of psychoactive compounds that induce hallucinogenic
effects by activating the serotonin 2A receptor (5-HT2AR). Clinical trials have demonstrated …
effects by activating the serotonin 2A receptor (5-HT2AR). Clinical trials have demonstrated …
The therapeutic potential of psilocybin
H Lowe, N Toyang, B Steele, H Valentine, J Grant, A Ali… - Molecules, 2021 - mdpi.com
The psychedelic effects of some plants and fungi have been known and deliberately
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …
exploited by humans for thousands of years. Fungi, particularly mushrooms, are the principal …
[HTML][HTML] Structure of a hallucinogen-activated Gq-coupled 5-HT2A serotonin receptor
Hallucinogens like lysergic acid diethylamide (LSD), psilocybin, and substituted N-benzyl
phenylalkylamines are widely used recreationally with psilocybin being considered as a …
phenylalkylamines are widely used recreationally with psilocybin being considered as a …
The experimental effects of psilocybin on symptoms of anxiety and depression: A meta-analysis
The current meta-analysis examined the effects of psilocybin in combination with behavioral
interventions on anxiety and depression in samples with elevated symptoms. Across four …
interventions on anxiety and depression in samples with elevated symptoms. Across four …
[HTML][HTML] Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders
Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …
highlighting the need for improved drug treatments. In this review an overview of drugs …
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants
Rationale Major depressive disorder is one of the leading global causes of disability, for
which the classic serotonergic psychedelics have recently reemerged as a potential …
which the classic serotonergic psychedelics have recently reemerged as a potential …
Attitudes and beliefs about the therapeutic use of psychedelic drugs among psychologists in the United States
Psychologists are a vital component of mental health treatment and their perceptions of
psychedelic-assisted therapy are critical for future implementation. This cross-sectional …
psychedelic-assisted therapy are critical for future implementation. This cross-sectional …
Psilocybin‐assisted group therapy in patients with cancer diagnosed with a major depressive disorder
M Agrawal, W Richards, Y Beaussant, S Shnayder… - Cancer, 2024 - Wiley Online Library
Background Depression is common in patients with cancer and is associated with lower
treatment adherence and reduced quality of life. Antidepressants and psychotherapy have …
treatment adherence and reduced quality of life. Antidepressants and psychotherapy have …
Therapeutic use of serotoninergic hallucinogens: a review of the evidence and of the biological and psychological mechanisms
RG Dos Santos, JEC Hallak - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Serotoninergic hallucinogens include drugs such as lysergic acid diethylamide (LSD),
dimethyltryptamine (DMT) and psilocybin. Recent trials with single/few doses of these …
dimethyltryptamine (DMT) and psilocybin. Recent trials with single/few doses of these …