The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X **e… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

Synthetic extracellular matrices with function-encoding peptides

C Ligorio, A Mata - Nature reviews bioengineering, 2023 - nature.com
The communication of cells with their surroundings is mostly encoded in the epitopes of
structural and signalling proteins present in the extracellular matrix (ECM). These peptide …

Stem cell–homing hydrogel-based miR-29b-5p delivery promotes cartilage regeneration by suppressing senescence in an osteoarthritis rat model

J Zhu, S Yang, Y Qi, Z Gong, H Zhang, K Liang… - Science …, 2022 - science.org
Osteoarthritis (OA) is a common joint disease characterized by progressive loss of cartilage
and reduction in lubricating synovial fluid, which lacks effective treatments currently. Here …

Neuro–bone tissue engineering: emerging mechanisms, potential strategies, and current challenges

W Sun, B Ye, S Chen, L Zeng, H Lu, Y Wan, Q Gao… - Bone research, 2023 - nature.com
The skeleton is a highly innervated organ in which nerve fibers interact with various skeletal
cells. Peripheral nerve endings release neurogenic factors and sense skeletal signals …

Short peptide nanofiber biomaterials ameliorate local hemostatic capacity of surgical materials and intraoperative hemostatic applications in clinics

Z Yang, L Chen, J Liu, H Zhuang, W Lin… - Advanced …, 2023 - Wiley Online Library
Short designer self‐assembling peptide (dSAP) biomaterials are a new addition to the
hemostat group. It may provide a diverse and robust toolbox for surgeons to integrate wound …

[HTML][HTML] Advances of Schwann cells in peripheral nerve regeneration: from mechanism to cell therapy

C Wei, Y Guo, Z Ci, M Li, Y Zhang, Y Zhou - Biomedicine & …, 2024 - Elsevier
Peripheral nerve injuries (PNIs) frequently occur due to various factors, including
mechanical trauma such as accidents or tool-related incidents, as well as complications …

Multifunctional biodegradable conductive hydrogel regulating microenvironment for stem cell therapy enhances the nerve tissue repair

C Xu, P Wu, K Yang, C Mu, B Li, X Li, Z Wang, Z Liu… - Small, 2024 - Wiley Online Library
The nerve guidance conduits incorporated with stem cells, which can differentiate into the
Schwann cells (SCs) to facilitate myelination, shows great promise for repairing the severe …

Self-assembling hydrogel structures for neural tissue repair

S Peressotti, GE Koehl, JA Goding… - … Biomaterials Science & …, 2021 - ACS Publications
Hydrogel materials have been employed as biological scaffolds for tissue regeneration
across a wide range of applications. Their versatility and biomimetic properties make them …

[HTML][HTML] Engineered hydrogels for peripheral nerve repair

Y Liu, X Zhang, C **ao, B Liu - Materials Today Bio, 2023 - Elsevier
Peripheral nerve injury (PNI) is a complex disease that often appears in young adults. It is
characterized by a high incidence, limited treatment options, and poor clinical outcomes …

[HTML][HTML] Bio-scaffolds as cell or exosome carriers for nerve injury repair

R Poongodi, YL Chen, TH Yang, YH Huang… - International journal of …, 2021 - mdpi.com
Central and peripheral nerve injuries can lead to permanent paralysis and organ
dysfunction. In recent years, many cell and exosome implantation techniques have been …