The midcycle surge of LH sets in motion interconnected networks of signaling cascades to
bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators …

This minireview summarizes the role that progesterone (P4) plays in regulating granulosa
and luteal cell function. These actions include the stimulation of P4 synthesis and the …

The molecular bridges that link the LH surge with functional changes in cumulus cells that
possess few LH receptors are being unraveled. Herein we document that epidermal growth …

Oocyte competence is the ability of the oocyte to complete maturation, undergo successful
fertilization, and reach the blastocyst stage. Cumulus cells are indispensable for this …

Progesterone (P4) receptor membrane component-1 (PGRMC1) and its binding partner,
plasminogen activator inhibitor 1 RNA binding protein (PAIRBP1) are thought to form a …

The present study investigates the regulation of small ubiquitin-related modifier-1 (SUMO-1)
expression in response to hypoxia in adult mouse brain and heart. We observed a …

BACKGROUND: Our objective was to characterize the tissular distribution of relevant
cytoskeletal proteins, cellular adhesion molecules and proliferation markers and conduct a …

The effects of gonadotropins on progesterone receptor (PR) expression and localization in
the mouse oviduct, uterus, and ovary was examined. In the oviduct ciliated epithelial cells of …

Progesterone (P4) exerts its effects by binding to specific genomic (nPR-A/B) and non-
genomic (mPRalpha/beta, PGRMC1/2) receptors. P4 has a role in the regulation of the …

ADAMTS-1 (a disintegrin and metalloproteinase with thrombospondin-like motifs) is a
multifunctional protease that is expressed in periovulatory follicles. Herein we show that …