The blood–brain barrier (BBB) is a continuous endothelial membrane within brain
microvessels that has sealed cell-to-cell contacts and is sheathed by mural vascular cells …

During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD)
considering the disease as a continuum. Thanks to evolving biomarker research and …

Thanks to its safety and accessibility, magnetic resonance imaging (MRI) is extensively used
in clinical routine and research field, largely contributing to our understanding of the …

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by
progressive neurodegeneration and cognitive decline. Understanding the pathophysiology …

Numerous studies have investigated the impacts of common types of chronic pain (CP) on
patients' cognitive function and observed that CP was associated with later dementia. More …

Hippocampal atrophy, as evidenced using magnetic resonance imaging (MRI), is one of the
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …

Mitochondrial dysfunction has been proposed to play a pivotal role in neurodegenerative
diseases, including Alzheimer's disease (AD). To address whether mitochondrial …

Alzheimer's disease (AD) is the most common cause of dementia, affecting the central
nervous system (CNS) through the accumulation of intraneuronal neurofibrillary tau tangles …

Brain imaging studies have shown that slow and progressive cerebral atrophy characterized
the development of Alzheimer's Disease (AD). Despite a large number of studies dedicated …

Dementia affects 47 million individuals worldwide, and assuming the status quo is projected
to rise to 150 million by 2050. Prevention of age-related cognitive impairment in older …