The number and genetic relatedness of transmitted/founder virus impact clinical outcome in vaginal R5 SHIVSF162P3N infection
L Tsai, I Tasovski, AR Leda, MPS Chin… - Retrovirology, 2014 - Springer
Background Severe genetic bottleneck occurs during HIV-1 sexual transmission whereby
most infections are initiated by a single transmitted/founder (T/F) virus. Similar observations …
most infections are initiated by a single transmitted/founder (T/F) virus. Similar observations …