Latest advances in cryogel technology for biomedical applications

A Memic, T Colombani, LJ Eggermont… - Advanced …, 2019 - Wiley Online Library
There exists a technological need for advanced materials with improved properties for
emerging biomedical applications. Recent developments in macroporous materials have …

A comprehensive review of cryogels and their roles in tissue engineering applications

KR Hixon, T Lu, SA Sell - Acta biomaterialia, 2017 - Elsevier
The extracellular matrix is fundamental in providing an appropriate environment for cell
interaction and signaling to occur. Replicating such a matrix is advantageous in the support …

Biomedical applications of polymeric cryogels

M Bakhshpour, N Idil, I Perçin, A Denizli - Applied Sciences, 2019 - mdpi.com
Featured Application This study presents the comprehensive applications of polymeric
cryogels in the field of biomedicine. To the best of our knowledge, this review is one of the …

Evaluating potential of tissue‐engineered cryogels and chondrocyte derived exosomes in articular cartilage repair

A Nikhil, A Kumar - Biotechnology and Bioengineering, 2022 - Wiley Online Library
Abstract Treatment of articular cartilage injuries especially osteochondral tissue requires
intervention of bioengineered scaffold. In this study, we investigated the potential of the …

Biocompatibility assessment of conducting PANI/chitosan nanofibers for wound healing applications

P Moutsatsou, K Coopman, S Georgiadou - Polymers, 2017 - mdpi.com
As electroactive polymers have recently presented potential in applications in the tissue
engineering and biomedical field, this study is aiming at the fabrication of composite …

Rational design of gelatin/nanohydroxyapatite cryogel scaffolds for bone regeneration by introducing chemical and physical cues to enhance osteogenesis of bone …

KT Shalumon, HT Liao, CY Kuo, CB Wong, CJ Li… - Materials Science and …, 2019 - Elsevier
Identification of key components in the chemical and physical milieu for directing
osteogenesis is a requirement in the investigation of tissue engineering scaffolds for …

Gelatin-modified bone substitute with bioactive molecules enhance cellular interactions and bone regeneration

AK Teotia, A Gupta, DB Raina, L Lidgren… - ACS applied materials …, 2016 - ACS Publications
In this work, we have synthesized injectable bone cement incorporated with gelatin to
enhance cellular interaction. Human osteosarcoma Saos-2 cells derived bone …

Promotion of the osteogenic activity of an antibacterial polyaniline coating by electrical stimulation

B Zhu, Y Li, F Huang, Z Chen, J **e, C Ding… - Biomaterials science, 2019 - pubs.rsc.org
Electrical stimulation (ES) exhibits a positive role in promoting the cell activity of osteoblasts.
Conducting polymers have the advantages of biocompatibility, good environmental stability …

Cryogel scaffolds from patient-specific 3D-printed molds for personalized tissue-engineered bone regeneration in pediatric cleft-craniofacial defects

KR Hixon, AM Melvin, AY Lin… - Journal of …, 2017 - journals.sagepub.com
Bone defects are extremely common in children with cleft-craniofacial conditions, especially
those with alveolar cleft defects and cranial defects. This study used patient-specific 3D …

Biocomposite macroporous cryogels as potential carrier scaffolds for bone active agents augmenting bone regeneration

DB Raina, H Isaksson, AK Teotia, L Lidgren… - Journal of controlled …, 2016 - Elsevier
Osteoinduction can be enhanced by combining scaffolds with bone morphogenic protein-2
(BMP-2). However, BMP's are known to also cause bone resorption. This can be controlled …