Hereditary haemorrhagic telangiectasia, inherited as an autosomal dominant trait, affects
approximately 1 in 5000 people. The abnormal vascular structures in HHT result from …

The autosomal-dominant trait hereditary haemorrhagic telangiectasia (HHT) affects 1 in 5–
8000 people. Genes mutated in HHT (most commonly for endoglin or activin receptor-like …

Background—Patent foramen ovale (PFO) is prevalent in patients with migraine with aura.
Observational studies show that PFO closure resulted in migraine cessation or improvement …

Pulmonary arteriovenous malformations (PAVMs) are abnormal direct vascular
communications between pulmonary arteries and veins which create high-flow right-to-left …

OBJECTIVE. Pulmonary arteriovenous malformations (PAVMs) are most often associated
with hereditary hemorrhagic telangiectasia. Untreated, they represent a serious threat due to …

Hereditary hemorrhagic telangiectasia (HHT) or Rendu-Osler-Weber disease is a genetic
disorder with autosomal dominance and variable penetrance, characterized by epistaxis …

Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant vascular disorder
characterized by severe and recurrent nosebleeds, mucocutaneous telangiectases, and, in …

Background Pulmonary first pass filtration of particles marginally exceeding∼ 7 µm (the size
of a red blood cell) is used routinely in diagnostics, and allows cellular aggregates forming …

Pulmonary right-to-left shunting can be encountered using transthoracic contrast
echocardiography (TTCE) with agitated saline. Diseases associated with pulmonary …

Background Transthoracic contrast echocardiography (TTCE) can detect pulmonary right-to-
left shunting (RLS) and is used to screen for pulmonary arteriovenous malformations …