Pulmonary diseases due to mycobacteria cause significant morbidity and mortality to human
health. In addition to tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), recent …

The field of point-of-care (POC) diagnostics offers the tantalizing possibility of providing
rapid diagnostic results in nonlaboratory settings. Here, we review progress in this research …

Tuberculosis (TB) is a major cause of deaths by a single infectious agent and has now been
a global public health problem due to increasing numbers of drug-resistant cases. Early and …

Infectious diseases are caused by pathogenic microorganisms and can be transmitted
between individuals and populations thus threatening the general public health and …

Background Accurate and rapid detection of tuberculosis (TB) and drug resistance are
critical for improving patient care and decreasing the spread of TB. Xpert® MTB/RIF assay …

Diagnosis of tuberculosis, and especially the diagnosis of extrapulmonary tuberculosis, still
faces challenges in clinical practice. There are several reasons for this. Methods based on …

Tuberculous meningitis is especially common in young children and people with untreated
HIV infection, and it kills or disables roughly half of everyone affected. Childhood disease …

Rapid progress has been made in the development of new diagnostic assays for
tuberculosis in recent years. New technologies have been developed and assessed, and …

Background The World Health Organization (WHO) and Foundation for Innovative New
Diagnostics (FIND) have published target product profiles (TPPs) calling for non-sputum …

Tuberculous meningitis (TBM) is the most severe form of tuberculosis. Microbiological
confirmation is rare, and treatment is often delayed, increasing mortality and morbidity. The …