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Cellular signalling pathways mediating the pathogenesis of chronic inflammatory respiratory diseases: an update
Respiratory disorders, especially non-communicable, chronic inflammatory diseases, are
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
amongst the leading causes of mortality and morbidity worldwide. Respiratory diseases …
[HTML][HTML] Personalized redox medicine in inflammatory bowel diseases: an emerging role for HIF-1α and NRF2 as therapeutic targets
Inflammatory bowel diseases (IBD), encompassing Crohn's disease (CD) and ulcerative
colitis (UC), are intimately associated with inflammation and overproduction of reactive …
colitis (UC), are intimately associated with inflammation and overproduction of reactive …
[HTML][HTML] Gold nanoparticles-embedded ceria with enhanced antioxidant activities for treating inflammatory bowel disease
M Li, J Liu, L Shi, C Zhou, M Zou, D Fu, Y Yuan, C Yao… - Bioactive Materials, 2023 - Elsevier
The excessive reactive oxygen species (ROS) is a hallmark associated with the initiation
and progression of inflammatory bowel disease (IBD), which execrably form a vicious cycle …
and progression of inflammatory bowel disease (IBD), which execrably form a vicious cycle …
Synthesis, characterization and in vitro assessment of colloidal gold nanoparticles of Gemcitabine with natural polysaccharides for treatment of breast cancer
L Devi, R Gupta, SK Jain, S Singh… - Journal of Drug Delivery …, 2020 - Elsevier
Targeted drug delivery plays an essential role in the treatment of breast cancer because it
provides therapeutic responses with low side effects for an extended period. In the present …
provides therapeutic responses with low side effects for an extended period. In the present …
[HTML][HTML] Neutrophil–epithelial crosstalk during intestinal inflammation
L Kang, X Fang, YH Song, ZX He, ZJ Wang… - Cellular and molecular …, 2022 - Elsevier
Neutrophils are the most abundant leukocyte population in the human circulatory system
and are rapidly recruited to sites of inflammation. Neutrophils play a multifaceted role in …
and are rapidly recruited to sites of inflammation. Neutrophils play a multifaceted role in …
Post-translational modifications of BRD4: therapeutic targets for tumor
N Liu, R Ling, X Tang, Y Yu, Y Zhou, D Chen - Frontiers in oncology, 2022 - frontiersin.org
Bromodomain-containing protein 4 (BRD4), a member of the bromodomain and
extraterminal (BET) family, is considered to be a major driver of cancer cell growth and a …
extraterminal (BET) family, is considered to be a major driver of cancer cell growth and a …
[HTML][HTML] Roles of Hypoxia-Inducible Factor-Prolyl Hydroxylases in Aging and Disease
The prolyl hydroxylase domain-containing (PHD or EGL9-homologs) enzyme family is
mainly known for its role in the cellular response to hypoxia. HIF-PH inhibitors can stabilize …
mainly known for its role in the cellular response to hypoxia. HIF-PH inhibitors can stabilize …
[HTML][HTML] Dietary crocin is protective in pancreatic cancer while reducing radiation-induced hepatic oxidative damage
Pancreatic cancer is one of the fatal causes of global cancer-related deaths. Although
surgery and chemotherapy are standard treatment options, post-treatment outcomes often …
surgery and chemotherapy are standard treatment options, post-treatment outcomes often …
Expression of HIF1α in intestinal epithelium restricts arthritis inflammation by inhibiting RIPK3-induced cell death machinery
P Lyu, J Wen, W Zhang, N Liu, I Stolzer… - Annals of the …, 2024 - ard.bmj.com
Objectives To investigate the mechanism by which intestinal epithelial cell (IEC) death
induces arthritis. Methods IEC death was assessed by staining for necroptosis and …
induces arthritis. Methods IEC death was assessed by staining for necroptosis and …
Recent advances in self-assembled nanoparticles for drug delivery
The collection of different bulk materials forms the nanoparticles, where the properties of the
nanoparticle are solely different from the individual components before being ensembled …
nanoparticle are solely different from the individual components before being ensembled …