Elements of the cytoskeleton interact intimately and communicate bidirectionally with cellular
membranes. Such interactions are critical for a host of cellular processes. Here we focus on …

10. Dickinson, RB, and Purich, DL (2002). Clamped-filament elongation model for actin-
based motors. Biophys. J. 82, 605–617. 11. Mogilner, A., and Oster, G.(2003). Force …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

Motile and morphogenetic cellular processes are driven by site-directed assembly of actin
filaments. Formins, proteins characterized by formin homology domains FH1 and FH2, are …

The motion of many intracellular pathogens is driven by the polymerization of actin filaments.
The propulsive force developed by the polymerization process is thought to arise from the …

Cells sustain high rates of actin filament elongation by maintaining a large pool of actin
monomers above the critical concentration for polymerization. Profilin–actin complexes …

The tightly coordinated, spatiotemporal control of actin filament remodeling provides the
basis of fundamental cellular processes, such as cell migration and adhesion. Specific …

Vasodilator‐stimulated phosphoprotein (VASP) is a key regulator of dynamic actin structures
like filopodia and lamellipodia, but its precise function in their formation is controversial …

Morphological changes in dendritic spines have been implicated in connective plasticity in
brain circuitry, but the underlying pathway leading from synaptic transmission to structural …

Mathematical and computational modeling is rapidly becoming an essential research
technique complementing traditional experimental biological methods. However, lack of …