ABSTRACT Introduction: Adverse drug reactions (ADRs) are a major health concern
worldwide. There are multiple causes of ADRs, some of which are preventable …

Breast cancer (BC) is one of the most prevalent types of cancer worldwide with high
morbidity and mortality rates. Treatment modalities include systemic therapy, in which …

Provides a timely update to a key textbook on human drug metabolism The third edition of
this comprehensive book covers basic concepts of teaching drug metabolism, starting from …

Background The liver plays a central role in the maintenance of homeostasis and health in
general. However, there is substantial inter-individual variation in hepatic gene expression …

The cardiotoxicity of certain chemotherapeutic agents is now well-established, and has led
to the development of the field of cardio-oncology, increased cardiac screening of cancer …

Chemotherapy is the mainstay in the treatment of breast cancer. However, many drugs that
are commonly used in clinical practice have a high incidence of side effects and multidrug …

The differences in patients' response to the same medication, toxicity included, are one of
the major problems in breast cancer treatment. Chemotherapy toxicity makes a significant …

Objectives Hematological toxicity induced by chemotherapy is known to be caused by
multiple factors, including genetic factors such as polymorphisms. The polymorphisms may …

Breast cancer (BC) is a heterogeneous and multifactorial disease. The system formed by
glutathione-S-transferases (GSTs) acts to protect the organism against the oxidative stress …

Background Oxidative stress genes are related to cancer development and treatment
response. In this study, we aimed to determine the predictive and prognostic roles of …