Cellular uptake of nanoparticles: journey inside the cell

S Behzadi, V Serpooshan, W Tao, MA Hamaly… - Chemical society …, 2017 - pubs.rsc.org
Nanoscale materials are increasingly found in consumer goods, electronics, and
pharmaceuticals. While these particles interact with the body in myriad ways, their beneficial …

Biodistribution, clearance, and long‐term fate of clinically relevant nanomaterials

J Bourquin, A Milosevic, D Hauser, R Lehner… - Advanced …, 2018 - Wiley Online Library
Realization of the immense potential of nanomaterials for biomedical applications will
require a thorough understanding of how they interact with cells, tissues, and organs. There …

Endocytosis and exocytosis of nanoparticles in mammalian cells

N Oh, JH Park - International journal of nanomedicine, 2014 - Taylor & Francis
Engineered nanoparticles that can be injected into the human body hold tremendous
potential to detect and treat complex diseases. Understanding of the endocytosis and …

The challenges of oral drug delivery via nanocarriers

J Reinholz, K Landfester, V Mailänder - Drug delivery, 2018 - Taylor & Francis
The oral application of pharmaceuticals is unarguably the most convenient method of
application. Especially for protein-or peptide-based drugs, however, the effectiveness is …

The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the …

F Wang, L Yu, MP Monopoli, P Sandin, E Mahon… - … , Biology and Medicine, 2013 - Elsevier
Nanoparticles have unique capacities of interacting with the cellular machinery and entering
cells. To be able to exploit this potential, it is essential to understand what controls the …

[HTML][HTML] Different endocytotic uptake mechanisms for nanoparticles in epithelial cells and macrophages

DA Kuhn, D Vanhecke, B Michen… - Beilstein journal of …, 2014 - beilstein-journals.org
Precise knowledge regarding cellular uptake of nanoparticles is of great importance for
future biomedical applications. Four different endocytotic uptake mechanisms, that is …

Photostable fluorescent organic dots with aggregation-induced emission (AIE dots) for noninvasive long-term cell tracing

K Li, W Qin, D Ding, N Tomczak, J Geng, R Liu, J Liu… - Scientific reports, 2013 - nature.com
Long-term noninvasive cell tracing by fluorescent probes is of great importance to life
science and biomedical engineering. For example, understanding genesis, development …

Exocytosis of nanoparticles from cells: role in cellular retention and toxicity

R Sakhtianchi, RF Minchin, KB Lee, AM Alkilany… - Advances in colloid and …, 2013 - Elsevier
Over the past decade, nanoparticles (NPs) have been increasingly developed in various
biomedical applications such as cell tracking, biosensing, contrast imaging, targeted drug …

Integration of in vitro and in vivo models to predict cellular and tissue dosimetry of nanomaterials using physiologically based pharmacokinetic modeling

Z Lin, S Aryal, YH Cheng, AJ Gesquiere - ACS nano, 2022 - ACS Publications
Nanomaterials (NMs) have been increasingly used in a number of areas, including
consumer products and nanomedicine. Target tissue dosimetry is important in the evaluation …

[HTML][HTML] Exocytosis of nanoparticles: a comprehensive review

J Liu, YY Liu, CS Li, A Cao, H Wang - Nanomaterials, 2023 - mdpi.com
Both biomedical applications and safety assessments of manufactured nanomaterials
require a thorough understanding of the interaction between nanomaterials and cells …