Mechanism of Candida pathogenesis: revisiting the vital drivers
Candida is the most implicated fungal pathogen in the clinical setting. Several factors play
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …
important roles in the pathogenesis of Candida spp. Multiple transcriptional circuits …
Candida albicans Heat Shock Proteins and Hsps-Associated Signaling Pathways as Potential Antifungal Targets
Y Gong, T Li, C Yu, S Sun - Frontiers in cellular and infection …, 2017 - frontiersin.org
In recent decades, the incidence of invasive fungal infections has increased notably.
Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on …
Candida albicans (C. albicans), a common opportunistic fungal pathogen that dwells on …
From environmental adaptation to host survival: Attributes that mediate pathogenicity of Candida auris
S Allert, D Schulz, P Kämmer, P Großmann, T Wolf… - Virulence, 2022 - Taylor & Francis
Candida species are a major cause of invasive fungal infections. While Candida albicans, C.
glabrata, C. parapsilosis, and C. tropicalis are the most dominant species causing life …
glabrata, C. parapsilosis, and C. tropicalis are the most dominant species causing life …
[PDF][PDF] Intracellular survival of Candida glabrata in macrophages: immune evasion and persistence
Candida glabrata is a successful human opportunistic pathogen which causes superficial
but also life-threatening systemic infections. During infection, C. glabrata has to cope with …
but also life-threatening systemic infections. During infection, C. glabrata has to cope with …
Inhibition of bacterial and fungal pathogens by the orphaned drug auranofin
BB Fuchs, R RajaMuthiah, ACR Souza… - Future medicinal …, 2016 - Taylor & Francis
Background: We identified auranofin as an antimicrobial compound utilizing a high-
throughput screen using a Caenorhabditis elegans–Staphylococcus aureus infection model …
throughput screen using a Caenorhabditis elegans–Staphylococcus aureus infection model …
Comparative study on alternative splicing in human fungal pathogens suggests its involvement during host invasion
P Sieber, K Voigt, P Kämmer, S Brunke… - Frontiers in …, 2018 - frontiersin.org
Alternative splicing (AS) is an important regulatory mechanism in eukaryotes but only little is
known about its impact in fungi. Human fungal pathogens are of high clinical interest …
known about its impact in fungi. Human fungal pathogens are of high clinical interest …
Transient mitochondria dysfunction confers fungal cross-resistance against phagocytic killing and fluconazole
S Siscar-Lewin, T Gabaldón, AM Aldejohann, O Kurzai… - MBio, 2021 - Am Soc Microbiol
Loss or inactivation of antivirulence genes is an adaptive strategy in pathogen evolution.
Candida glabrata is an important opportunistic pathogen related to baker's yeast, with the …
Candida glabrata is an important opportunistic pathogen related to baker's yeast, with the …
Neutrophil activation by Candida glabrata but not Candida albicans promotes fungal uptake by monocytes
S Duggan, F Essig, K Hünniger, Z Mokhtari… - Cellular …, 2015 - Wiley Online Library
C andida albicans and C andida glabrata account for the majority of candidiasis cases
worldwide. Although both species are in the same genus, they differ in key virulence …
worldwide. Although both species are in the same genus, they differ in key virulence …
The Effectiveness of Voriconazole in Therapy of Candida glabrata's Biofilms Oral Infections and Its Influence on the Matrix Composition and Gene Expression
Candida glabrata is one of most prevalent yeast in fungal infections, especially in
immunocompromised patients. Its azole resistance results in a low therapeutic response …
immunocompromised patients. Its azole resistance results in a low therapeutic response …
Moonlight-like proteins of the cell wall protect sessile cells of Candida from oxidative stress
I Serrano-Fujarte, E López-Romero… - Microbial …, 2016 - Elsevier
Biofilms of Candida species are associated with high morbidity and hospital mortality.
Candida forms biofilms by adhering to human host epithelium through cell wall proteins …
Candida forms biofilms by adhering to human host epithelium through cell wall proteins …