Put a ring on it: application of small aliphatic rings in medicinal chemistry
MR Bauer, P Di Fruscia, SCC Lucas… - RSC Medicinal …, 2021 - pubs.rsc.org
Aliphatic three-and four-membered rings including cyclopropanes, cyclobutanes, oxetanes,
azetidines and bicyclo [1.1. 1] pentanes have been increasingly exploited in medicinal …
azetidines and bicyclo [1.1. 1] pentanes have been increasingly exploited in medicinal …
Stronger Brønsted acids: recent progress
T Akiyama, K Mori - Chemical reviews, 2015 - ACS Publications
In contrast to Lewis-acid catalysts, Brønsted acids have been employed primarily as
catalysts for the formation and cleavage of C− O bonds, such as hydrolysis and formation of …
catalysts for the formation and cleavage of C− O bonds, such as hydrolysis and formation of …
Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions
P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …
Macrocycles as ion pair receptors
Cation and anion recognition have both played central roles in the development of
supramolecular chemistry. Much of the associated research has focused on the …
supramolecular chemistry. Much of the associated research has focused on the …
Functionalized Zr-UiO-67 metal-organic frameworks: Structural landscape and application
UiO based metal-organic frameworks (MOFs) have attracted much attention of many
scientists among the large family of Zirconium MOFs. UiO-series including UiO-66,-67 and …
scientists among the large family of Zirconium MOFs. UiO-series including UiO-66,-67 and …
Applications of asymmetric organocatalysis in medicinal chemistry
In the last decade, organocatalysis, the use of small chiral organic molecules as catalysts,
has proven to be a valuable and attractive tool for the synthesis of enantiomerically enriched …
has proven to be a valuable and attractive tool for the synthesis of enantiomerically enriched …
[HTML][HTML] Fluorescent and colorimetric sensors for anions: Highlights from 2020 to 2022
The development of colorimetric and fluorescent sensors continues apace. In this review, we
highlight developments made in this area from 2020 to 2022. The review is structured by the …
highlight developments made in this area from 2020 to 2022. The review is structured by the …
Catalytic asymmetric synthesis of 1, 2-diamines
F Foubelo, C Nájera, MG Retamosa… - Chemical Society …, 2024 - pubs.rsc.org
The asymmetric catalytic synthesis of 1, 2-diamines has received considerable interest,
especially in the last ten years, due to their presence in biologically active compounds and …
especially in the last ten years, due to their presence in biologically active compounds and …
Discovery of a novel amino lipid that improves lipid nanoparticle performance through specific interactions with mRNA
Lipid nanoparticles (LNPs) are capable of delivering messenger ribonucleic acid (mRNA)
efficiently and systemically as a result of both particle composition and architecture. The …
efficiently and systemically as a result of both particle composition and architecture. The …
The versatility of squaramides: From supramolecular chemistry to chemical biology
This review covers recent advances in the use of the squaramide moiety in chemical
research. We focus on the varied applications of squaramides under the broad headings of …
research. We focus on the varied applications of squaramides under the broad headings of …