Put a ring on it: application of small aliphatic rings in medicinal chemistry

MR Bauer, P Di Fruscia, SCC Lucas… - RSC Medicinal …, 2021 - pubs.rsc.org
Aliphatic three-and four-membered rings including cyclopropanes, cyclobutanes, oxetanes,
azetidines and bicyclo [1.1. 1] pentanes have been increasingly exploited in medicinal …

Stronger Brønsted acids: recent progress

T Akiyama, K Mori - Chemical reviews, 2015 - ACS Publications
In contrast to Lewis-acid catalysts, Brønsted acids have been employed primarily as
catalysts for the formation and cleavage of C− O bonds, such as hydrolysis and formation of …

Bifunctional amine‐squaramides: powerful hydrogen‐bonding organocatalysts for asymmetric domino/cascade reactions

P Chauhan, S Mahajan, U Kaya… - … Synthesis & Catalysis, 2015 - Wiley Online Library
Organocatalytic domino/cascade reactions provide a convenient method for the construction
of complex molecular structures bearing multiple stereocenters in a highly stereoselective …

Macrocycles as ion pair receptors

Q He, GI Vargas-Zúñiga, SH Kim, SK Kim… - Chemical …, 2019 - ACS Publications
Cation and anion recognition have both played central roles in the development of
supramolecular chemistry. Much of the associated research has focused on the …

Functionalized Zr-UiO-67 metal-organic frameworks: Structural landscape and application

AH Vahabi, F Norouzi, E Sheibani… - Coordination Chemistry …, 2021 - Elsevier
UiO based metal-organic frameworks (MOFs) have attracted much attention of many
scientists among the large family of Zirconium MOFs. UiO-series including UiO-66,-67 and …

Applications of asymmetric organocatalysis in medicinal chemistry

J Alemán, S Cabrera - Chemical Society Reviews, 2013 - pubs.rsc.org
In the last decade, organocatalysis, the use of small chiral organic molecules as catalysts,
has proven to be a valuable and attractive tool for the synthesis of enantiomerically enriched …

[HTML][HTML] Fluorescent and colorimetric sensors for anions: Highlights from 2020 to 2022

G Picci, R Montis, AM Gilchrist, PA Gale… - Coordination Chemistry …, 2024 - Elsevier
The development of colorimetric and fluorescent sensors continues apace. In this review, we
highlight developments made in this area from 2020 to 2022. The review is structured by the …

Catalytic asymmetric synthesis of 1, 2-diamines

F Foubelo, C Nájera, MG Retamosa… - Chemical Society …, 2024 - pubs.rsc.org
The asymmetric catalytic synthesis of 1, 2-diamines has received considerable interest,
especially in the last ten years, due to their presence in biologically active compounds and …

Discovery of a novel amino lipid that improves lipid nanoparticle performance through specific interactions with mRNA

M Cornebise, E Narayanan, Y **a… - Advanced Functional …, 2022 - Wiley Online Library
Lipid nanoparticles (LNPs) are capable of delivering messenger ribonucleic acid (mRNA)
efficiently and systemically as a result of both particle composition and architecture. The …

The versatility of squaramides: From supramolecular chemistry to chemical biology

LA Marchetti, LK Kumawat, N Mao, JC Stephens… - Chem, 2019 - cell.com
This review covers recent advances in the use of the squaramide moiety in chemical
research. We focus on the varied applications of squaramides under the broad headings of …