Plasmids, a molecular cornerstone of antimicrobial resistance in the One Health era

S Castañeda-Barba, EM Top, T Stalder - Nature Reviews Microbiology, 2024 - nature.com
Antimicrobial resistance (AMR) poses a substantial threat to human health. The widespread
prevalence of AMR is, in part, due to the horizontal transfer of antibiotic resistance genes …

[HTML][HTML] Biological effects of quinolones: a family of broad-spectrum antimicrobial agents

AR Millanao, AY Mora, NA Villagra, SA Bucarey… - Molecules, 2021 - mdpi.com
Broad antibacterial spectrum, high oral bioavailability and excellent tissue penetration
combined with safety and few, yet rare, unwanted effects, have made the quinolones class of …

Joint effects of bacterium and biochar in remediation of antibiotic-heavy metal contaminated soil and responses of resistance gene and microbial community

X Zhang, Z Gong, G Allinson, X Li, C Jia - Chemosphere, 2022 - Elsevier
Soils containing both veterinary antibiotics (VAs) and heavy metals necessitate effective
remediation approaches, and microbial and molecular levels of the results should be further …

Distribution and genetic characterization of fluoroquinolone resistance gene qnr among Salmonella strains from chicken in China

Y Chen, L Liu, Y Guo, J Chu, B Wang, Y Sui… - Microbiology …, 2024 - journals.asm.org
The prevalence and dissemination of the plasmid-mediated fluoroquinolone (FQ) resistance
gene qnr in Salmonella are considered serious public health concerns worldwide. So far, no …

[HTML][HTML] Metagenomics insights into microbiome and antibiotic resistance genes from free living amoeba in chlorinated wastewater effluents

T Conco-Biyela, MA Malla, OO Awolusi, M Allam… - International Journal of …, 2024 - Elsevier
Free living amoeba (FLA) are among the organisms commonly found in wastewater and are
well-established hosts for diverse microbial communities. Despite its clinical significance …

[HTML][HTML] Effects of subinhibitory quinolone concentrations on functionality, microbial community composition, and abundance of antibiotic resistant bacteria and qnrS in …

K Slipko, RBM Marano, E Cytryn, V Merkus… - Journal of …, 2021 - Elsevier
Wastewater treatment plants (WWTPs) are continuously exposed to sub-inhibitory
concentrations of antibiotics that are thought to contribute to the spreading of antibiotic …

Phenotypic and genotypic characteristics of Escherichia coli with non-susceptibility to quinolones isolated from environmental samples on pig farms

P Kindle, K Zurfluh, M Nüesch-Inderbinen… - Porcine health …, 2019 - Springer
Background In the last decade, the growth of the pig-farming industry has led to an increase
in antibiotic use, including several used in human medicine, eg (fluoro) quinolones. Data …

[PDF][PDF] Biofilm Formation and Plasmid-Mediated Quinolone Resistance Genes at Varying Quinolone Inhibitory Concentrations in Quinolone-Resistant Bacteria …

A Basnet, AB Chand, S Bajracharya… - The American Journal …, 2024 - researchgate.net
The likelihood of antimicrobial failure in COVID-19 patients with bacterial superinfection
arises from both phenotypic (biofilms) and genotypic mechanisms. This cross-sectional …

Novel class 1 integron harboring antibiotic resistance genes in wastewater-derived bacteria as revealed by functional metagenomics

BB McGivern, RK McDonell, SK Morris, TM LaPara… - Plasmid, 2021 - Elsevier
Combatting antibiotic resistance is critical to our ability to treat infectious diseases. Here, we
identified and characterized diverse antimicrobial resistance genes, including potentially …

[PDF][PDF] A combined metagenomics and metatranscriptomics approach to assess the occurrence and reduction of pathogenic bacteria in municipal wastewater …

T Conco - 2023 - openscholar.dut.ac.za
The emergence and spread of pathogens, antibiotic resistant bacteria (ARB) and antibiotic
resistant genes (ARG) through insufficiently treated effluents from wastewater treatment …