Over the past two decades, bile acids (BAs) have become established as important
signaling molecules that enable fine-tuned inter-tissue communication from the liver, their …

The trillions of microorganisms in the gut microbiome have attracted much attention recently
owing to their sophisticated and widespread impacts on numerous aspects of host …

Multidrug-resistant organism (MDRO) colonization is a fundamental challenge in
antimicrobial resistance. Limited studies have shown that fecal microbiota transplantation …

Secondary bile acids (SBAs) are derived from primary bile acids (PBAs) in a process reliant
on biosynthetic capabilities possessed by few microbes. To evaluate the role of BAs in …

The opportunistic pathogen Enterococcus faecium colonizes humans and a wide range of
animals, endures numerous stresses, resists antibiotic treatment and stubbornly persists in …

The genus Enterococcus consists of facultative Gram-positive cocci that have been isolated
from a variety of animals, plants and environmental sources. Although fifty-eight species …

Bile acids are prominent host and microbiota metabolites that modulate host immunity and
microbial pathogenesis. However, the mechanisms by which bile acids suppress microbial …

Host-microbiota interactions are bidirectional. On one hand, ecological pressures exerted by
the host shape the composition and function of the microbiota. On the other, resident …

Background Recent metagenomic analyses have revealed dysbiosis of the gut microbiota of
ulcerative colitis (UC) patients. However, the impacts of this dysbiosis are not fully …

Enterococci are commensals of the intestinal tract of many animals and humans. Of the
various known and still unnamed new enterococcal species, only isolates of Enterococcus …