Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder

S Nisar, M Haris - Molecular psychiatry, 2023 - nature.com
Autism-spectrum disorders (ASDs) are developmental disabilities that manifest in early
childhood and are characterized by qualitative abnormalities in social behaviors …

Neural functions of hypothalamic oxytocin and its regulation

P Wang, SC Wang, X Liu, S Jia, X Wang, T Li… - ASN …, 2022 - journals.sagepub.com
Oxytocin (OT), a nonapeptide, has a variety of functions. Despite extensive studies on OT
over past decades, our understanding of its neural functions and their regulation remains …

Sex and age differences in “theory of mind” across 57 countries using the English version of the “Reading the Mind in the Eyes” Test

DM Greenberg, V Warrier, A Abu-Akel, C Allison… - Proceedings of the …, 2023 - pnas.org
The “Reading the Mind in the Eyes” Test (Eyes Test) is a widely used assessment of “theory
of mind.” The NIMH Research Domain Criteria recommends it as one of two tests for …

Infrequent intranasal oxytocin followed by positive social interaction improves symptoms in autistic children: a pilot randomized clinical trial

J Le, L Zhang, W Zhao, S Zhu, C Lan, J Kou… - Psychotherapy and …, 2022 - karger.com
Introduction: There are currently no approved drug interventions for social behavior
dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily …

Roles of the oxytocin receptor (OXTR) in human diseases

K Pierzynowska, L Gaffke, M Żabińska, Z Cyske… - International journal of …, 2023 - mdpi.com
The oxytocin receptor (OXTR), encoded by the OXTR gene, is responsible for the signal
transduction after binding its ligand, oxytocin. Although this signaling is primarily involved in …

Oxytocin receptor gene (OXTR) polymorphisms and social, emotional and behavioral functioning in children and adolescents: a systematic narrative review

J Kohlhoff, S Cibralic, DJ Hawes, V Eapen - Neuroscience & Biobehavioral …, 2022 - Elsevier
This study systematically reviewed available evidence regarding associations between
polymorphisms of the oxytocin receptor (OXTR) gene and socio-emotional and behavioral …

Bridging Genetic Insights with Neuroimaging in Autism Spectrum Disorder—A Systematic Review

J Vilela, C Rasga, JX Santos, H Martiniano… - International Journal of …, 2024 - mdpi.com
Autism Spectrum Disorder (ASD) is an early onset neurodevelopmental disorder
characterized by impaired social interaction and communication, and repetitive patterns of …

Patterns of neural activity in response to threatening faces are predictive of autistic traits: modulatory effects of oxytocin receptor genotype

X Zheng, F Zhou, M Fu, L Xu, J Wang, J Li, K Li… - Translational …, 2024 - nature.com
Autistic individuals generally demonstrate impaired emotion recognition but it is unclear
whether effects are emotion-specific or influenced by oxytocin receptor (OXTR) genotype …