The potential of carbonic anhydrase enzymes as a novel target for anti-cancer treatment

Z **ao-Qun, M **an-Li, NS Ariffin - European Journal of Pharmacology, 2024 - Elsevier
Carbonic anhydrase (CA) is a zinc-dependent metal enzyme that maintains the pH and
carbon dioxide (CO 2) homeostasis in cells by catalyzing the reversible hydration and …

Hybrid Sono-Photodynamic Combination Therapy Mediated by Water-Soluble Gallium Phthalocyanine Enhances the Cytotoxic Effect against Breast Cancer Cell …

A Turkkol, C Can Karanlık, SG Calıskan… - ACS Applied Bio …, 2024 - ACS Publications
Breast cancer is a life-threatening disease that is gaining increasing importance due to its
rising incidence, highlighting the need for novel treatment methods with the least …

Synthesis, enzyme inhibition, and molecular docking studies of a novel chalcone series bearing benzothiazole scaffold

AB Musatat, A Atahan, A Ergün… - Biotechnology and …, 2023 - Wiley Online Library
This study reports the facile synthesis of a novel series of benzothiazole‐chalcones, in
addition to their inhibitory profile on important metabolic enzymes including human carbonic …

Potential thiosemicarbazone‐based enzyme inhibitors: Assessment of antiproliferative activity, metabolic enzyme inhibition properties, and molecular docking …

H Yakan, ÜM Koçyiğit, H Muğlu, M Ergul… - … of Biochemical and …, 2022 - Wiley Online Library
A new series of thiosemicarbazone derivatives (1–11) were prepared from various
aldehydes and isocyanates with high yields and practical methods. The structures of these …

New sulfonylhydrazones containing methane sulfonic acid hydrazıde havıng human anticarbonic anhydrase and antimicrobıal activıty: synthesis, spectroscopic …

D Uzun, E Erdoğdu, AB Gündüzalp… - Macedonian Journal of …, 2021 - mjcce.org.mk
In this work, new sulfonylhydrazones nomenclatured as 3, 5-ditertbutylsalicylaldehyde
methanesulfonylhydrazone (II), 3-tertbutylsalicylaldehyde methanesulfonylhydrazone (III) …

Benzotiyazol Türevi Kalkonların Sentezi, Biyolojik Aktivite, Teorik Hesaplama Ve Moleküler Yerleştirme Çalışmaları

AB Musatat - 2023 - search.proquest.com
Flavonoid ailesinin üyeleri çok çeşitli biyolojik aktivitelere sahiptir ve doğal bileşiklerin bu
grubu meyveler, bitkiler, tohumlar, yapraklar ve birçok çiçekte bulunmaktadır. Doğal veya …

New Sulfonylhydrazones Contaınıng Methane Sulfonıc Acıd Hydrazıde Havıng Human Antı-Carbonıc Anhydrase And Antımıcrobıal Actıvıty: Synthesıs, Spectroscopıc …

D Uzun, E Erdoğdu, AB Gündüzalp, ÜÖ Özdemir… - 2021 - openaccess.ahievran.edu.tr
In this work, new sulfonylhydrazones nomenclatured as 3, 5-ditertbutylsalicylaldehyde
methanesulfonylhydrazone (II), 3-tertbutylsalicylaldehyde methanesulfonylhydrazone (III) …