Somatostatin and its receptor family
YC Patel - Frontiers in neuroendocrinology, 1999 - Elsevier
Somatostatin (SST), a regulatory peptide, is produced by neuroendocrine, inflammatory, and
immune cells in response to ions, nutrients, neuropeptides, neurotransmitters, thyroid and …
immune cells in response to ions, nutrients, neuropeptides, neurotransmitters, thyroid and …
Peptide receptors as molecular targets for cancer diagnosis and therapy
JC Reubi - Endocrine reviews, 2003 - academic.oup.com
During the past decade, proof of the principle that peptide receptors can be used
successfully for in vivo targeting of human cancers has been provided. The molecular basis …
successfully for in vivo targeting of human cancers has been provided. The molecular basis …
The cells of the islets of Langerhans
G Da Silva Xavier - Journal of clinical medicine, 2018 - mdpi.com
Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A
number of new studies have pointed to the potential for conversion of non-β islet cells in to …
number of new studies have pointed to the potential for conversion of non-β islet cells in to …
Systemic complications of acromegaly and the impact of the current treatment landscape: an update
MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …
increased mortality when not adequately treated. Substantial advances in acromegaly …
The new biology and pharmacology of glucagon
In the last two decades we have witnessed sizable progress in defining the role of
gastrointestinal signals in the control of glucose and energy homeostasis. Specifically, the …
gastrointestinal signals in the control of glucose and energy homeostasis. Specifically, the …
Somatostatin receptor sst1–sst5 expression in normal and neoplastic human tissues using receptor autoradiography with subtype-selective ligands
Somatostatin receptors are known to be expressed in a large number of human tumours and
represent the basis for in vivo tumour targeting. Stable somatostatin derivatives such as …
represent the basis for in vivo tumour targeting. Stable somatostatin derivatives such as …
Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity
M Rocheville, DC Lange, U Kumar, SC Patel, RC Patel… - Science, 2000 - science.org
Somatostatin and dopamine are two major neurotransmitter systems that share a number of
structural and functional characteristics. Somatostatin receptors and dopamine receptors are …
structural and functional characteristics. Somatostatin receptors and dopamine receptors are …
α-Cells of the endocrine pancreas: 35 years of research but the enigma remains
J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - academic.oup.com
Glucagon, a hormone secreted from the α-cells of the endocrine pancreas, is critical for
blood glucose homeostasis. It is the major counterpart to insulin and is released during …
blood glucose homeostasis. It is the major counterpart to insulin and is released during …
Physiology of the pancreatic α-cell and glucagon secretion: role in glucose homeostasis and diabetes
Angiogenesis is an important component in the development of thyroid goitre. Vascular
endothelial growth factor (VEGF) represents a family of specific endothelial cell mitogens …
endothelial growth factor (VEGF) represents a family of specific endothelial cell mitogens …
Comparison of 68Ga-DOTATOC PET and 111In-DTPAOC (Octreoscan) SPECT in patients with neuroendocrine tumours
I Buchmann, M Henze, S Engelbrecht… - European journal of …, 2007 - Springer
Abstract Purpose Neuroendocrine tumours (NETs) can be imaged with scintigraphy using
radiolabelled somatostatin analogues. The aim of our study was to compare the value of 68 …
radiolabelled somatostatin analogues. The aim of our study was to compare the value of 68 …