Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution

AA Pollen, U Kilik, CB Lowe, JG Camp - Nature Reviews Genetics, 2023 - nature.com
Our ancestors acquired morphological, cognitive and metabolic modifications that enabled
humans to colonize diverse habitats, develop extraordinary technologies and reshape the …

[HTML][HTML] The contribution of Neanderthal introgression to modern human traits

PF Reilly, A Tjahjadi, SL Miller, JM Akey, S Tucci - Current Biology, 2022 - cell.com
Neanderthals, our closest extinct relatives, lived in western Eurasia from 400,000 years ago
until they went extinct around 40,000 years ago. DNA retrieved from ancient specimens …

Phylogenomic analyses highlight innovation and introgression in the continental radiations of Fagaceae across the Northern Hemisphere

BF Zhou, S Yuan, AA Crowl, YY Liang, Y Shi… - Nature …, 2022 - nature.com
Northern Hemisphere forests changed drastically in the early Eocene with the diversification
of the oak family (Fagaceae). Cooling climates over the next 20 million years fostered the …

Human genetic history on the Tibetan Plateau in the past 5100 years

H Wang, MA Yang, S Wangdue, H Lu, H Chen, L Li… - Science …, 2023 - science.org
Using genome-wide data of 89 ancient individuals dated to 5100 to 100 years before the
present (BP) from 29 sites across the Tibetan Plateau, we found plateau-specific ancestry …

Middle and Late Pleistocene Denisovan subsistence at Baishiya Karst Cave

H **a, D Zhang, J Wang, Z Fagernäs, T Li, Y Li, J Yao… - nature, 2024 - nature.com
Genetic and fragmented palaeoanthropological data suggest that Denisovans were once
widely distributed across eastern Eurasia,–. Despite limited archaeological evidence, this …

A weakly structured stem for human origins in Africa

AP Ragsdale, TD Weaver, EG Atkinson, EG Hoal… - Nature, 2023 - nature.com
Despite broad agreement that Homo sapiens originated in Africa, considerable uncertainty
surrounds specific models of divergence and migration across the continent. Progress is …

Functional EPAS1/HIF2A missense variant is associated with hematocrit in Andean highlanders

ES Lawrence, W Gu, RJ Bohlender… - Science …, 2024 - science.org
Hypoxia-inducible factor pathway genes are linked to adaptation in both human and
nonhuman highland species. EPAS1, a notable target of hypoxia adaptation, is associated …

Ancient genomes from the Himalayas illuminate the genetic history of Tibetans and their Tibeto-Burman speaking neighbors

CC Liu, D Witonsky, A Gosling, JH Lee… - Nature …, 2022 - nature.com
Present-day Tibetans have adapted both genetically and culturally to the high altitude
environment of the Tibetan Plateau, but fundamental questions about their origins remain …

More than a decade of genetic research on the Denisovans

S Peyrégne, V Slon, J Kelso - Nature Reviews Genetics, 2024 - nature.com
Denisovans, a group of now extinct humans who lived in Eastern Eurasia in the Middle and
Late Pleistocene, were first identified from DNA sequences just over a decade ago. Only ten …

Past climate change effects on human evolution

A Timmermann, P Raia, A Mondanaro… - Nature Reviews Earth & …, 2024 - nature.com
The genus Homo evolved during the Pleistocene—an epoch of gradual cooling and
amplification of glacial cycles. The changing climates influenced early human survival …